ID A0A1B0VGW7_FERIS Unreviewed; 440 AA.
AC A0A1B0VGW7;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=RNA-guided endonuclease IscB {ECO:0000313|EMBL:AMW31893.1};
GN Name=iscB {ECO:0000313|EMBL:AMW31893.1};
GN ORFNames=NA23_00035 {ECO:0000313|EMBL:AMW31893.1};
OS Fervidobacterium islandicum.
OC Bacteria; Thermotogota; Thermotogae; Thermotogales; Fervidobacteriaceae;
OC Fervidobacterium.
OX NCBI_TaxID=2423 {ECO:0000313|EMBL:AMW31893.1, ECO:0000313|Proteomes:UP000093740};
RN [1] {ECO:0000313|EMBL:AMW31893.1, ECO:0000313|Proteomes:UP000093740}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AW-1 {ECO:0000313|EMBL:AMW31893.1,
RC ECO:0000313|Proteomes:UP000093740};
RX PubMed=26421103; DOI=10.1186/s40793-015-0063-4;
RA Lee Y.J., Jeong H., Park G.S., Kwak Y., Lee S.J., Lee S.J., Park M.K.,
RA Kim J.Y., Kang H.K., Shin J.H., Lee D.W.;
RT "Genome sequence of a native-feather degrading extremely thermophilic
RT Eubacterium, Fervidobacterium islandicum AW-1.";
RL Stand. Genomic Sci. 10:71-71(2015).
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DR EMBL; CP014334; AMW31893.1; -; Genomic_DNA.
DR RefSeq; WP_033191570.1; NZ_CP014334.2.
DR AlphaFoldDB; A0A1B0VGW7; -.
DR STRING; 2423.NA23_00035; -.
DR KEGG; fia:NA23_00035; -.
DR eggNOG; COG1403; Bacteria.
DR OrthoDB; 9779761at2; -.
DR Proteomes; UP000093740; Chromosome.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00085; HNHc; 1.
DR Gene3D; 1.10.30.50; -; 1.
DR InterPro; IPR002711; HNH.
DR InterPro; IPR003615; HNH_nuc.
DR InterPro; IPR047693; RNA-guided_IscB-like.
DR InterPro; IPR025938; RRXRR_dom.
DR NCBIfam; NF040563; guided_IscB; 1.
DR PANTHER; PTHR33877:SF2; HNH NUCLEASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR33877; SLL1193 PROTEIN; 1.
DR Pfam; PF01844; HNH; 1.
DR Pfam; PF14239; RRXRR; 1.
DR SMART; SM00507; HNHc; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:AMW31893.1};
KW Hydrolase {ECO:0000313|EMBL:AMW31893.1};
KW Nuclease {ECO:0000313|EMBL:AMW31893.1}.
FT DOMAIN 185..236
FT /note="HNH nuclease"
FT /evidence="ECO:0000259|SMART:SM00507"
SQ SEQUENCE 440 AA; 50450 MW; 777FF23FD0412A65 CRC64;
MVFVLDKNKK PLMPCSEKRA RLLLSRGRAV VHKMHPFTIR LKDRTVQQSE LQPLRLKLDQ
GAKVTGLSVL REDGDVAETV FLCEIHHKTD IKQKLDARRA VRRSRRNRKT RYRKPRFLNR
RRPEGWLPPS FNARADQLIN AVRKLTKLLP ISAISIEDAK FDTQKLQNPE ISGIEYQRGT
LFGYEVREYL LEKWGRRCAY CGRSDVPLEI DHIVPRSRGG TDRVSNLTLA CHECNQKKSN
KTAAEFGCPH IEERARQTYK QAAFMNSIRS YLSKSLSSFG IPVEYGTGAL TKANRIRLGF
PKEHYFDACC VGESTSSEIR ITQSYVQIWC AVGRGTRQMC NTDKFGFPRG HRQRCKKHFG
FQTGDIVKAI VPRGKYAGIW MGMVAVRGSG FFDIKDKNGK RVCQGIRYKY CKLIQTADGW
QYSKTKTNYS ISHTTEVACI
//
