ID A0A1B1AT95_9ACTN Unreviewed; 429 AA.
AC A0A1B1AT95;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Arsenic transporter {ECO:0000313|EMBL:ANP49793.1};
GN ORFNames=AVL59_09385 {ECO:0000313|EMBL:ANP49793.1};
OS Streptomyces griseochromogenes.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=68214 {ECO:0000313|EMBL:ANP49793.1, ECO:0000313|Proteomes:UP000092659};
RN [1] {ECO:0000313|EMBL:ANP49793.1, ECO:0000313|Proteomes:UP000092659}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14511 {ECO:0000313|EMBL:ANP49793.1,
RC ECO:0000313|Proteomes:UP000092659};
RA Wu L.;
RT "Complete genome sequence of Streptomyces griseochromogenes ATCC 14511, the
RT Blasticidin S producer.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CitM (TC 2.A.11) transporter family.
CC {ECO:0000256|ARBA:ARBA00009843}.
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DR EMBL; CP016279; ANP49793.1; -; Genomic_DNA.
DR RefSeq; WP_067301455.1; NZ_JAGGLP010000009.1.
DR AlphaFoldDB; A0A1B1AT95; -.
DR STRING; 68214.AVL59_09385; -.
DR KEGG; sgs:AVL59_09385; -.
DR OrthoDB; 9774335at2; -.
DR Proteomes; UP000092659; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015105; F:arsenite transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0046685; P:response to arsenic-containing substance; IEA:UniProtKB-KW.
DR InterPro; IPR000802; Arsenical_pump_ArsB.
DR InterPro; IPR004680; Cit_transptr-like_dom.
DR PANTHER; PTHR43302; TRANSPORTER ARSB-RELATED; 1.
DR PANTHER; PTHR43302:SF5; TRANSPORTER ARSB-RELATED; 1.
DR Pfam; PF03600; CitMHS; 1.
DR PRINTS; PR00758; ARSENICPUMP.
PE 3: Inferred from homology;
KW Arsenical resistance {ECO:0000256|ARBA:ARBA00022849};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 11..362
FT /note="Citrate transporter-like"
FT /evidence="ECO:0000259|Pfam:PF03600"
SQ SEQUENCE 429 AA; 44412 MW; 3558197C12741899 CRC64;
MRVLLRLHVL DRVAIGLLVI GLLCVATGLL PTGSASDAMT RIAPLLPFLG TVIVLAELTS
RAEVFDVLAA RMARAGRGSY PLLFLLCVAF ASVTTIALNL DTTAVLLTPV MLALASRVGI
APVPLAMTTV WLANTASLLL PVSNLTNLLA ANRVALSPLG LAGRMWAPQL AAVAVTMACL
WLFFWRRGRR GAEEDATGTG SADLVGVSVS GPGAARADDV RPRATDRYAP PEVHSPADPV
LFRACALACA GFLLAILVAD VPLWTASATA AAVAVAAFAV RRPSVLRPSL IPWRLLVMVP
GMFLVVETVN AHGLHDLLAS AVGHDGGVLG MFRAAAVGGG LSNALNNLPV YLAGEAAVPV
ANHDQLLALL VGTNAGPVIT PWASLATLLW YERCHAYGVR VPVARLMGTG AVLATAAVVT
SVTALALTR
//
