ID   A0A1B1B7W9_9ACTN        Unreviewed;       397 AA.
AC   A0A1B1B7W9;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE            EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN   ORFNames=AVL59_39820 {ECO:0000313|EMBL:ANP54925.1};
OS   Streptomyces griseochromogenes.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=68214 {ECO:0000313|EMBL:ANP54925.1, ECO:0000313|Proteomes:UP000092659};
RN   [1] {ECO:0000313|EMBL:ANP54925.1, ECO:0000313|Proteomes:UP000092659}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14511 {ECO:0000313|EMBL:ANP54925.1,
RC   ECO:0000313|Proteomes:UP000092659};
RA   Wu L.;
RT   "Complete genome sequence of Streptomyces griseochromogenes ATCC 14511, the
RT   Blasticidin S producer.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP016279; ANP54925.1; -; Genomic_DNA.
DR   RefSeq; WP_067314284.1; NZ_JAGGLP010000006.1.
DR   AlphaFoldDB; A0A1B1B7W9; -.
DR   STRING; 68214.AVL59_39820; -.
DR   KEGG; sgs:AVL59_39820; -.
DR   OrthoDB; 7294637at2; -.
DR   Proteomes; UP000092659; Chromosome.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           27..397
FT                   /note="exo-alpha-sialidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5039515463"
FT   DOMAIN          62..370
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
SQ   SEQUENCE   397 AA;  42365 MW;  D10CE6A5141B9955 CRC64;
     MTPLHRTLLT TLALLTSLTA RLPAHATPAH ASSGCTTSVP YVSGAGGYHT YRIPAMVRTG
     HGTVLAFAEG RHDGAGDSGD IDVVLRRSAD GGCTWGPLTV VAAGEGNTRG NPAPVVDPRS
     GAVVLVTSYN SGAVTEAQIM RGETGEERGR RVFVQRSWDD GRHFTSPKEI TAEVKRRGWR
     WYATGPGHGV ALTRGPHTGR LLIPANHSAA PPAGSHDTGV ESKYYGGHAL YSDDEGRTWH
     LGFVDDTYDG VTNANETSAA QLPDGRVYFN SRQQNGKAVG HRIDAYSRDG GQTLERPYAV
     QPTLNDVPVV QGSVLQLHGH EAPLLFSAPS VPTARRAMAL WSSTDDGHTF TKLQTLSAER
     AAYSDLVQLG SDTVGVLYET GAKGTYDTIE FRRLSVP
//