ID A0A1B1BJ44_9MICO Unreviewed; 640 AA.
AC A0A1B1BJ44;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=PA27867_1569 {ECO:0000313|EMBL:ANP72526.1};
OS Cryobacterium arcticum.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Cryobacterium.
OX NCBI_TaxID=670052 {ECO:0000313|EMBL:ANP72526.1, ECO:0000313|Proteomes:UP000092582};
RN [1] {ECO:0000313|EMBL:ANP72526.1, ECO:0000313|Proteomes:UP000092582}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAMC 27867 {ECO:0000313|EMBL:ANP72526.1,
RC ECO:0000313|Proteomes:UP000092582};
RA Lee J., Kim O.-S.;
RT "Genome sequencing of Cryobacterium arcticum PAMC 27867.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR EMBL; CP016282; ANP72526.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B1BJ44; -.
DR STRING; 670052.PA27867_1569; -.
DR KEGG; cart:PA27867_1569; -.
DR PATRIC; fig|670052.7.peg.1625; -.
DR Proteomes; UP000092582; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd06577; PASTA_pknB; 4.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.30.10.20; -; 4.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR NCBIfam; NF033483; PknB_PASTA_kin; 1.
DR PANTHER; PTHR45832:SF24; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45832; SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED; 1.
DR Pfam; PF03793; PASTA; 3.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00740; PASTA; 3.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51178; PASTA; 3.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ANP72526.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Serine/threonine-protein kinase {ECO:0000313|EMBL:ANP72526.1};
KW Transferase {ECO:0000313|EMBL:ANP72526.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 341..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 10..266
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 366..431
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 503..570
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 571..637
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
SQ SEQUENCE 640 AA; 66934 MW; A909A6EDE2D802B8 CRC64;
MIGRLIDGRY QVRSRIARGG MATVYLATDL RLERRVAIKI MHGHLADDNA FRSRFIQEAR
SAARLAHPNV VNVFDQGQDA DIAYLVMEHL PGITLRDLLK DYGRLTPEQT MDILEAVLSG
LAAAHKAGIV HRDVKPENVL LADDGRIKIG DFGLARAVNN NTATGQALLG TVAYLSPELV
TRGIADARSD IYALGIMTYE MLTGEQPYVG EAPMQVAYQH ANDTVPMPSL VAPGVPQELD
ELVLWATARD PEERPRDARV MLDQLLDVEK LVRPNDQTAM QATMVLPRSV VATSADAETQ
ILGRAPLAAA ATLIAPDPET GEVDSTDQLA GTTQKRRRRG YWLFTLIVLL AALAGGAGWY
FGVGPGSEIA VPSLTSASPE EATAQLEALG LVAAPGTAYS TEIPAGLVVG TNPGDGTRVA
KGSTVTVNVS QGPAPIVLPT LAGLTPDAAA TAISDALAVP GTVDEIFSNT VKKGLVISAT
RDSDGGDVSQ GGDSFEGATI NYAVSLGDVT DVTGQTLEDA IDTLADQDLE GRSGPETYSE
TVAKGKVISA APASGGPLRK GSVITLTVSR GPEPVEVPDV VGQGWSEAKN TLTDLGFKLS
YNPGADAIAA LLSVASTDPV AGTSLPKGST ITLKPTNPFG
//
