ID A0A1B1E845_9APIC Unreviewed; 2694 AA.
AC A0A1B1E845;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=FH2 domain-containing protein {ECO:0000259|PROSITE:PS51444};
GN ORFNames=PCOAH_00055020 {ECO:0000313|EMBL:ANQ11163.1};
OS Plasmodium coatneyi.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium.
OX NCBI_TaxID=208452 {ECO:0000313|EMBL:ANQ11163.1, ECO:0000313|Proteomes:UP000092716};
RN [1] {ECO:0000313|Proteomes:UP000092716}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hackeri {ECO:0000313|Proteomes:UP000092716};
RA Chien J.-T., Pakala S.B., Geraldo J.A., Lapp S.A., Barnwell J.W.,
RA Kissinger J.C., Galinski M.R., Humphrey J.C.;
RT "First high quality genome sequence of Plasmodium coatneyi using continuous
RT long reads from single molecule, real-time sequencing.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP016252; ANQ11163.1; -; Genomic_DNA.
DR RefSeq; XP_019917858.1; XM_020062282.1.
DR EnsemblProtists; ANQ11163; ANQ11163; PCOAH_00055020.
DR GeneID; 30912236; -.
DR VEuPathDB; PlasmoDB:PCOAH_00055020; -.
DR OrthoDB; 231882at2759; -.
DR Proteomes; UP000092716; Chromosome 14.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR PANTHER; PTHR45725:SF1; DELPHILIN; 1.
DR PANTHER; PTHR45725; FORMIN HOMOLOGY 2 FAMILY MEMBER; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 2003..2406
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 91..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 414..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 668..810
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 900..1013
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1212..1323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1589..1641
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1887..1973
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2557..2597
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1675..1702
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2321..2348
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 106..140
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 443..489
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 678..692
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..746
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 747..766
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1244..1266
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1267..1281
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1282..1311
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1622..1641
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1936..1958
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2694 AA; 308537 MW; 4263A127E0FE2D6D CRC64;
MRNHLERNAK GTTEKKDQRF NTNGKEKEEE ERGYGMNTIY HEPVGEMEAR RIDSFSRKKR
VAKETLWNIE NLEENDENMI CFKNFVEKDL SDDNEGGSRS RNGSWDGSEN RSECRRDSRH
EKMITLNNKG RNRDPPRDSK HNPTTGQILT NYMLVPDEIR HKYTKTYLFQ ISKRLLVMKK
PWRLPKNVEL QINNVYHLSN YIKVLERISS EYLNEPPINY YYKGLELYNK NVFANIDYLL
KKVDIKKNPK NFEFRNLIKI NECYYDLSTF GKSPSAMLYQ SYVIWDIHGS SLTLEQEYEN
FFDSQIMDYS FGEREYPNLK YILSICSSVL FWLNFNKKDN FAIINYHKIS SFILLIFSCV
MLVIDNTLTF AQIQEILYKS SKISNSDKED EEDNIHTNIS SNYFGNKYES ESFSNEEKSD
DTCNTLGGGK KQKGRHYRIL PHRRKENLQG DKYVNRNGHR YDNEEDTSPR SNSYKDKHLD
KDSYRNKRET SDSVHIYNFS NGESEDYPTY DNHFNGGDMT FATDEYKSHN PIGDYNKMQY
HTLNLNGKSE EYDNEVEISQ NRKKKTKFSN SWGFDLTNRE KYKSNNKVKD HHFWIPFDYW
KSSHKRYFFY IYELMKNKNK KVENVPFKLK SIIFSDYVMC SVSVEVYEII YKDNQEFHLD
VLSDCGGDTA AEEGSTGEGT MDDQSVISES SSEGSKNRRH DQCNNHNEHN EVDQSNEESK
GEGLLDDETF YRDSSLKGKL KRGTPNERDS SGTLNRRGSS DYSNEMIHPA GSVKNRNGKI
CGVYKPVGRK SSRDKIPHGE SEAPSRLSVP KGDLNANSIF INSKNKPTAC ERNKLRRTSS
YYKLRNGSNC CSDSYEGASF NTANLSDLSD SVISSSEPTY ERSVPDKQYE VGRAERRPFD
LRSGKSPITH KIRQHGGKYY SPRSLSSISP EPTSVDYMDR YRNEDIPGSG NIQRGRSKGK
KTTNGKVKTK SCTYHPQRKI KNSIESDESL SPMMKKPTSD APKGGETEHK KDSKWKEKKI
YDFLRRNRNK KQKKGEDRNK GVSSAKSGYE YFLKCNNLSY NVVSSYEKNK KKYVTIDFTH
DAEGNTKEHI ICGDILILIG HKNIEKFHKG FSSSYSFHTG FLKKASSEVL HIRKEDMDIN
SNYQSYIPDG MKLSIILDSA NKKDCMKEYK RNLKNHNKME DLRSLRNFEK NKSFESNDSE
VALYGLRGSE TGISASGVGS HNGGETSARG KGGRGENSDE QDEEGEAKWW KGRNGHNVMK
CRRGEEESDD EEEDDEECIE QPCEQHNDKE DELNDPTHHR RETKRTPQQR EPRNKPILSN
SKQMDFHSKI NYSGYSIFSE KEPKIKYNAT NITQLLTSLF GFKNREDKYS LINKQNVCSL
LSSKRSFSNL ISLKDYLQRQ YEVITNPTES MYHFVQNHVL KVNIPLVQYL KKITHLSNLK
IYFSLKLCNN DLSKSLNFIV SIWGIHILKK KSSIRYSSTL NELPEFREEF KKIVTHEVDI
KTRTELAGHV NHADSTNVSC TNEDVYEKLD SSANLLKEHE QVEADDEVDV VLSKEPCRKV
SSLHRLEETF EWTRELGKFM HLKELHPYRE SETVSSTSGA EREETSEAKI GTQNEVTRSE
PNEAPGKTKP KEPATHKVQM EDRSEVITNI DGIKIAKMEI NKAYYQMREE TNFAKSEEQT
DFRKKEKEKE KVQENIEKTI EDNESFLKSM VEKEKPSKAI EETSTKSDVL KKIEESNFFY
AKLPSGELVK LKVKDKNEVG TYESMPLLLI EPVDDSGHLT RAMSGLPMKE ESNKNESATL
DKAANKDRLI NDSEKMYDQM VMKRSSVESM LSVESDRSTM SRYSTSVVVP PPVFIPKGEV
SVGEKVEVKM GEKMDLAVVV KPPQPAAKEL PKQLPKQPAS EGQTKPKAVE AVLKKAKEKR
PPPPLPPALL KRAPPKATTE GKEPGGDTKK ESSVKPGMPK KMGKKMPGPP PPLPPSLLSK
VKMGEKAKMG MKKCPMSFAP KKFAKVQEKR PLGIKLHWQL LPTHKIEGTV FNEIKSQEAK
YNLIDTKAVH KLFARVKGEK KIVKKVTEEK KKSSEEKLIT VLDRTRAQNI GILLRFPMST
QEIVQKISVF DLENMNTEFL QKVLHILPTK EESDSILQKL EHENVKEENF RDVERKLIPF
IYMDKCQCKI EICLFSLKYE KMINEISKDL DIYDKAVNEV RSSIRLRSLL NAVLKWGNYV
NYGVNENEDL VALGFTLSSV LKLTEFKSSI DNTITSLHYI TVSLCTYLPN LNMNLLQTDL
NSVSVASKMS SETVDILLSS LDKEINYIRE QLKCPYEDVF KEKMKNILQD SEMKYANAQK
RYEETKKSVQ QLGTYLGEDM SKGANLEGIF IILSSIVDNF TKCYKDILAN PKKFSIMLND
ENLLDDYYTF FGKKKNKNLP SSKNYTPLSK EAVTKEQGAT KESGKEIGKI RINRLNSCIG
IVRKNDNAKS SMFQLRNKLM QDIQNRAFIK RANSDGDKLE CKPTILLSNQ KDTPIPNTGL
RENNAGAENA QSLNGNGNGV NAKGENVPHG CALGGELKRG ENSTGNVNDE TMLGQKKPIG
SVNDETMLGQ KKPIGSVNDE TMEKDETMLG QKKPIGNAND ETKLGVDNPL GTVNKERRLI
EGLNCDEKPN GDINAEVNLA EGPKIETKPN ASTKIEDKIN DERGGLVIED KIVE
//
