ID A0A1B1M184_STRLN Unreviewed; 498 AA.
AC A0A1B1M184;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=HEAT repeat domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=GJU35_00985 {ECO:0000313|EMBL:QMV04383.1}, GJU35_43935
GN {ECO:0000313|EMBL:QMV11941.1}, SLCG_0157
GN {ECO:0000313|EMBL:AXG51312.1}, SLINC_0162
GN {ECO:0000313|EMBL:ANS62386.1};
OS Streptomyces lincolnensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1915 {ECO:0000313|EMBL:ANS62386.1, ECO:0000313|Proteomes:UP000092598};
RN [1] {ECO:0000313|EMBL:ANS62386.1, ECO:0000313|Proteomes:UP000092598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2936 {ECO:0000313|EMBL:ANS62386.1,
RC ECO:0000313|Proteomes:UP000092598};
RA Meng S.C.;
RT "Enhancement of antibiotic productionsby engineered nitrateutilization in
RT actinobacteria.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AXG51312.1, ECO:0000313|Proteomes:UP000253884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LC-G {ECO:0000313|EMBL:AXG51312.1,
RC ECO:0000313|Proteomes:UP000253884};
RX PubMed=29574602; DOI=10.1007/s10295-018-2029-1;
RA Xu Y., Tan G., Ke M., Li J., Tang Y., Meng S., Niu J., Wang Y., Liu R.,
RA Wu H., Bai L., Zhang L., Zhang B.;
RT "Enhanced lincomycin production by co-overexpression of metK1 and metK2 in
RT Streptomyces lincolnensis.";
RL J. Ind. Microbiol. Biotechnol. 45:345-355(2018).
RN [3] {ECO:0000313|EMBL:QMV04383.1, ECO:0000313|Proteomes:UP000515335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B48 {ECO:0000313|EMBL:QMV04383.1,
RC ECO:0000313|Proteomes:UP000515335};
RX PubMed=32322696;
RA Wang R., Kong F., Wu H., Hou B., Kang Y., Cao Y., Duan S., Ye J., Zhang H.;
RT "Complete genome sequence of high-yield strain S. lincolnensis B48 and
RT identification of crucial mutations contributing to lincomycin
RT overproduction.";
RL Synth Syst Biotechnol 5:37-48(2020).
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DR EMBL; CP016438; ANS62386.1; -; Genomic_DNA.
DR EMBL; CP022744; AXG51312.1; -; Genomic_DNA.
DR EMBL; CP046024; QMV04383.1; -; Genomic_DNA.
DR EMBL; CP046024; QMV11941.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B1M184; -.
DR STRING; 1915.SLINC_0162; -.
DR KEGG; sls:SLINC_0162; -.
DR PATRIC; fig|1915.4.peg.226; -.
DR OrthoDB; 4160491at2; -.
DR Proteomes; UP000092598; Chromosome.
DR Proteomes; UP000253884; Chromosome.
DR Proteomes; UP000515335; Chromosome.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR004155; PBS_lyase_HEAT.
DR PANTHER; PTHR12697:SF5; DEOXYHYPUSINE HYDROXYLASE; 1.
DR PANTHER; PTHR12697; PBS LYASE HEAT-LIKE PROTEIN; 1.
DR Pfam; PF13646; HEAT_2; 2.
DR SMART; SM00567; EZ_HEAT; 5.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000092598}.
SQ SEQUENCE 498 AA; 53269 MW; 615E590F0D46762E CRC64;
MTTEHQVAFF LRELETGDTW RRAAAAKGLG KLGGAEHAAA LVRAAADPAP EVREGAAVGL
GRLGVPEAGA EVLPALMDDD DPWVRRRASL ASIRLGLSDR EVVDAYGRLL GDPDYHLRIN
ALEALQELGV PGDVPALVRL LGDPAHGIGG RAWAMVRVFR EDRDVEAELV RTAQWGEDAA
RAGALLLLPE QHIERLLPSL LRDLTDAPST EVRRATVFRL ASVDRPEVQD ALLAALEAER
DPEMAAQLLY LLARSGDERL LGPASRWLSK ESAGPSAAFT LGSVGGKTAT KLLRGALTDP
TTPACTLAAA AMAYGEMGRW DAVWLLLPLL GHAEREVYGG ALRGLDAMAD TGFRPWERAA
VARALVARLG VAPTLVGVAE RVLAGLAEAL PGVRELVDRT TSPLVRAAAL SLLDPHNATD
AGTPHDLPLF VRHLDDVDWW VRQAAAKGIA HWVEETGTLP PGEERLRDRL TALDADPIDS
VREAAAEALR ALDGCRNN
//
