ID A0A1B1M381_STRLN Unreviewed; 322 AA.
AC A0A1B1M381;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=LLM class flavin-dependent oxidoreductase {ECO:0000313|EMBL:QMV04808.1};
DE SubName: Full=Luciferase-like monooxygenase {ECO:0000313|EMBL:ANS62872.1};
GN ORFNames=GJU35_03445 {ECO:0000313|EMBL:QMV04808.1}, SLCG_0641
GN {ECO:0000313|EMBL:AXG51796.1}, SLINC_0648
GN {ECO:0000313|EMBL:ANS62872.1};
OS Streptomyces lincolnensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1915 {ECO:0000313|EMBL:ANS62872.1, ECO:0000313|Proteomes:UP000092598};
RN [1] {ECO:0000313|EMBL:ANS62872.1, ECO:0000313|Proteomes:UP000092598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2936 {ECO:0000313|EMBL:ANS62872.1,
RC ECO:0000313|Proteomes:UP000092598};
RA Meng S.C.;
RT "Enhancement of antibiotic productionsby engineered nitrateutilization in
RT actinobacteria.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AXG51796.1, ECO:0000313|Proteomes:UP000253884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LC-G {ECO:0000313|EMBL:AXG51796.1,
RC ECO:0000313|Proteomes:UP000253884};
RX PubMed=29574602; DOI=10.1007/s10295-018-2029-1;
RA Xu Y., Tan G., Ke M., Li J., Tang Y., Meng S., Niu J., Wang Y., Liu R.,
RA Wu H., Bai L., Zhang L., Zhang B.;
RT "Enhanced lincomycin production by co-overexpression of metK1 and metK2 in
RT Streptomyces lincolnensis.";
RL J. Ind. Microbiol. Biotechnol. 45:345-355(2018).
RN [3] {ECO:0000313|EMBL:QMV04808.1, ECO:0000313|Proteomes:UP000515335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B48 {ECO:0000313|EMBL:QMV04808.1,
RC ECO:0000313|Proteomes:UP000515335};
RX PubMed=32322696;
RA Wang R., Kong F., Wu H., Hou B., Kang Y., Cao Y., Duan S., Ye J., Zhang H.;
RT "Complete genome sequence of high-yield strain S. lincolnensis B48 and
RT identification of crucial mutations contributing to lincomycin
RT overproduction.";
RL Synth Syst Biotechnol 5:37-48(2020).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP016438; ANS62872.1; -; Genomic_DNA.
DR EMBL; CP022744; AXG51796.1; -; Genomic_DNA.
DR EMBL; CP046024; QMV04808.1; -; Genomic_DNA.
DR RefSeq; WP_067426513.1; NZ_CP046024.1.
DR AlphaFoldDB; A0A1B1M381; -.
DR STRING; 1915.SLINC_0648; -.
DR KEGG; sls:SLINC_0648; -.
DR PATRIC; fig|1915.4.peg.776; -.
DR OrthoDB; 675245at2; -.
DR Proteomes; UP000092598; Chromosome.
DR Proteomes; UP000253884; Chromosome.
DR Proteomes; UP000515335; Chromosome.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR Gene3D; 3.20.20.30; Luciferase-like domain; 1.
DR InterPro; IPR011251; Luciferase-like_dom.
DR InterPro; IPR036661; Luciferase-like_sf.
DR PANTHER; PTHR43244; -; 1.
DR PANTHER; PTHR43244:SF1; 5,10-METHYLENETETRAHYDROMETHANOPTERIN REDUCTASE; 1.
DR Pfam; PF00296; Bac_luciferase; 1.
DR SUPFAM; SSF51679; Bacterial luciferase-like; 1.
PE 4: Predicted;
KW Monooxygenase {ECO:0000313|EMBL:ANS62872.1};
KW Oxidoreductase {ECO:0000313|EMBL:ANS62872.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000092598}.
FT DOMAIN 19..300
FT /note="Luciferase-like"
FT /evidence="ECO:0000259|Pfam:PF00296"
SQ SEQUENCE 322 AA; 34314 MW; 34A13EE037B5B499 CRC64;
MSPQDASGTI GVLLPRDIPH ADLIPFAQEA DDYGFGELWV VEDLGYRGGL VQAATVLART
RRIRVGVGLL PAAARNVAFA AMEAATLAQL HPGRLDLAVG HGMPDWMRSA GAWPASPLTL
LGEYIHTLKT LLAGRPADMD GRYVRLDGLC LDPSVLPEHV PDIFAGVRGP KSLALSGEVA
DGTLLAEPVS PEYVRHALTS INAQRPHRIA TYNITVVDDD PHAALATARP ALAPLGDPDW
APHIVPLGFH DELAALRRTS KSAQEFAQAI PEEWAHRLAL TGTPDHVRAR IQDLFTSGVT
TAVLSPVGPD YRSALAGLAK VL
//
