ID A0A1B1M4B0_STRLN Unreviewed; 374 AA.
AC A0A1B1M4B0;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Oxidoreductase {ECO:0000313|EMBL:ANS63488.1};
DE SubName: Full=SidA/IucD/PvdA family monooxygenase {ECO:0000313|EMBL:QMV05368.1};
GN ORFNames=GJU35_06700 {ECO:0000313|EMBL:QMV05368.1}, SLCG_1255
GN {ECO:0000313|EMBL:AXG52410.1}, SLINC_1264
GN {ECO:0000313|EMBL:ANS63488.1};
OS Streptomyces lincolnensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1915 {ECO:0000313|EMBL:ANS63488.1, ECO:0000313|Proteomes:UP000092598};
RN [1] {ECO:0000313|EMBL:ANS63488.1, ECO:0000313|Proteomes:UP000092598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2936 {ECO:0000313|EMBL:ANS63488.1,
RC ECO:0000313|Proteomes:UP000092598};
RA Meng S.C.;
RT "Enhancement of antibiotic productionsby engineered nitrateutilization in
RT actinobacteria.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AXG52410.1, ECO:0000313|Proteomes:UP000253884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LC-G {ECO:0000313|EMBL:AXG52410.1,
RC ECO:0000313|Proteomes:UP000253884};
RX PubMed=29574602; DOI=10.1007/s10295-018-2029-1;
RA Xu Y., Tan G., Ke M., Li J., Tang Y., Meng S., Niu J., Wang Y., Liu R.,
RA Wu H., Bai L., Zhang L., Zhang B.;
RT "Enhanced lincomycin production by co-overexpression of metK1 and metK2 in
RT Streptomyces lincolnensis.";
RL J. Ind. Microbiol. Biotechnol. 45:345-355(2018).
RN [3] {ECO:0000313|EMBL:QMV05368.1, ECO:0000313|Proteomes:UP000515335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B48 {ECO:0000313|EMBL:QMV05368.1,
RC ECO:0000313|Proteomes:UP000515335};
RX PubMed=32322696;
RA Wang R., Kong F., Wu H., Hou B., Kang Y., Cao Y., Duan S., Ye J., Zhang H.;
RT "Complete genome sequence of high-yield strain S. lincolnensis B48 and
RT identification of crucial mutations contributing to lincomycin
RT overproduction.";
RL Synth Syst Biotechnol 5:37-48(2020).
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DR EMBL; CP016438; ANS63488.1; -; Genomic_DNA.
DR EMBL; CP022744; AXG52410.1; -; Genomic_DNA.
DR EMBL; CP046024; QMV05368.1; -; Genomic_DNA.
DR RefSeq; WP_067427911.1; NZ_CP046024.1.
DR AlphaFoldDB; A0A1B1M4B0; -.
DR STRING; 1915.SLINC_1264; -.
DR KEGG; sls:SLINC_1264; -.
DR PATRIC; fig|1915.4.peg.1451; -.
DR OrthoDB; 178899at2; -.
DR Proteomes; UP000092598; Chromosome.
DR Proteomes; UP000253884; Chromosome.
DR Proteomes; UP000515335; Chromosome.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR43539:SF78; FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR43539; FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220); 1.
DR Pfam; PF13738; Pyr_redox_3; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE 4: Predicted;
KW Monooxygenase {ECO:0000313|EMBL:QMV05368.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000092598}.
FT REGION 354..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 374 AA; 40601 MW; 5DA45008E7881A2D CRC64;
MNNTREVEVV VIGAGQAGLS SAYHLRRTGF EPERDFVVLD HSPGPGGAWQ FRWPSLTYGK
VHGMHSLPGM ELTDADPARP SSQVVAEYFT AYESAFGLRV RRPVDVRAVR DGGEGGRLLV
ETSDGTWSTR TLINATGTWD RPFWPRYPGQ ETFRGRQLHT ARYPGPEAFA GRRVVVVGGG
ASGTQHLMEL APYAAATTWV TRRPPVFREG PFTEDVGRAA VALVEERVRR GLPPRSVVSV
TGLPLDDAVR QAIADGVLDR QPMFDRITPD GVQWRDGRRV EADVILWATG FRPAVDHLAP
LKLREPGGGI RAEGTRAVAD PRIHLVGYGP SASTIGANRA GRAAVRDIRR LSAAEPARAA
QRADTARPTV SVAA
//
