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Database: UniProt
Entry: A0A1B1M4M1_STRLN
LinkDB: A0A1B1M4M1_STRLN
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ID   A0A1B1M4M1_STRLN        Unreviewed;       103 AA.
AC   A0A1B1M4M1;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   10-APR-2019, entry version 13.
DE   RecName: Full=Urease subunit beta {ECO:0000256|HAMAP-Rule:MF_01954};
DE            EC=3.5.1.5 {ECO:0000256|HAMAP-Rule:MF_01954};
DE   AltName: Full=Urea amidohydrolase subunit beta {ECO:0000256|HAMAP-Rule:MF_01954};
GN   Name=ureB {ECO:0000256|HAMAP-Rule:MF_01954};
GN   ORFNames=SLCG_1388 {ECO:0000313|EMBL:AXG52543.1}, SLINC_1397
GN   {ECO:0000313|EMBL:ANS63621.1};
OS   Streptomyces lincolnensis.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1915 {ECO:0000313|EMBL:ANS63621.1, ECO:0000313|Proteomes:UP000092598};
RN   [1] {ECO:0000313|EMBL:ANS63621.1, ECO:0000313|Proteomes:UP000092598}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 2936 {ECO:0000313|EMBL:ANS63621.1,
RC   ECO:0000313|Proteomes:UP000092598};
RA   Meng S.C.;
RT   "Enhancement of antibiotic productionsby engineered nitrateutilization
RT   in actinobacteria.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AXG52543.1, ECO:0000313|Proteomes:UP000253884}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LC-G {ECO:0000313|EMBL:AXG52543.1,
RC   ECO:0000313|Proteomes:UP000253884};
RX   PubMed=29574602; DOI=10.1007/s10295-018-2029-1;
RA   Xu Y., Tan G., Ke M., Li J., Tang Y., Meng S., Niu J., Wang Y.,
RA   Liu R., Wu H., Bai L., Zhang L., Zhang B.;
RT   "Enhanced lincomycin production by co-overexpression of metK1 and
RT   metK2 in Streptomyces lincolnensis.";
RL   J. Ind. Microbiol. Biotechnol. 45:345-355(2018).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+);
CC         Xref=Rhea:RHEA:20557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16199, ChEBI:CHEBI:16526, ChEBI:CHEBI:28938;
CC         EC=3.5.1.5; Evidence={ECO:0000256|HAMAP-Rule:MF_01954,
CC         ECO:0000256|SAAS:SAAS01115728};
CC   -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3)
CC       from urea (urease route): step 1/1. {ECO:0000256|HAMAP-
CC       Rule:MF_01954, ECO:0000256|SAAS:SAAS00779045}.
CC   -!- SUBUNIT: Heterotrimer of UreA (gamma), UreB (beta) and UreC
CC       (alpha) subunits. Three heterotrimers associate to form the active
CC       enzyme. {ECO:0000256|HAMAP-Rule:MF_01954,
CC       ECO:0000256|SAAS:SAAS00779069}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01954}.
CC   -!- SIMILARITY: Belongs to the urease beta subunit family.
CC       {ECO:0000256|HAMAP-Rule:MF_01954, ECO:0000256|SAAS:SAAS00779065}.
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DR   EMBL; CP016438; ANS63621.1; -; Genomic_DNA.
DR   EMBL; CP022744; AXG52543.1; -; Genomic_DNA.
DR   RefSeq; WP_067428171.1; NZ_CP022744.1.
DR   EnsemblBacteria; ANS63621; ANS63621; SLINC_1397.
DR   KEGG; sls:SLINC_1397; -.
DR   PATRIC; fig|1915.4.peg.1596; -.
DR   KO; K01429; -.
DR   OrthoDB; 1755809at2; -.
DR   BioCyc; GCF_001685355:G1EY5-1513-MONOMER; -.
DR   UniPathway; UPA00258; UER00370.
DR   Proteomes; UP000092598; Chromosome.
DR   Proteomes; UP000253884; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009039; F:urease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00407; Urease_beta; 1.
DR   Gene3D; 2.10.150.10; -; 1.
DR   HAMAP; MF_01954; Urease_beta; 1.
DR   InterPro; IPR002019; Urease_beta.
DR   InterPro; IPR036461; Urease_betasu_sf.
DR   Pfam; PF00699; Urease_beta; 1.
DR   SUPFAM; SSF51278; SSF51278; 1.
DR   TIGRFAMs; TIGR00192; urease_beta; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000092598,
KW   ECO:0000313|Proteomes:UP000253884};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01954};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_01954,
KW   ECO:0000256|SAAS:SAAS00779062};
KW   Reference proteome {ECO:0000313|Proteomes:UP000092598}.
SQ   SEQUENCE   103 AA;  10666 MW;  3395F5AC33301C14 CRC64;
     MIPGEFLFAS GPIVYNEGLD VTALTVLNAA DRPVQVGSHY HFAEANPGLD FDRAAARGKR
     LNIAAGTAVR FEPGIPVDVE LVPLAGARVV PGLRGETGGA LDA
//
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