ID A0A1B1M537_STRLN Unreviewed; 382 AA.
AC A0A1B1M537;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Integral membrane protein {ECO:0000313|EMBL:ANS63760.1};
GN ORFNames=SLCG_1528 {ECO:0000313|EMBL:AXG52683.1}, SLINC_1536
GN {ECO:0000313|EMBL:ANS63760.1};
OS Streptomyces lincolnensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1915 {ECO:0000313|EMBL:ANS63760.1, ECO:0000313|Proteomes:UP000092598};
RN [1] {ECO:0000313|EMBL:ANS63760.1, ECO:0000313|Proteomes:UP000092598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2936 {ECO:0000313|EMBL:ANS63760.1,
RC ECO:0000313|Proteomes:UP000092598};
RA Meng S.C.;
RT "Enhancement of antibiotic productionsby engineered nitrateutilization in
RT actinobacteria.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AXG52683.1, ECO:0000313|Proteomes:UP000253884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LC-G {ECO:0000313|EMBL:AXG52683.1,
RC ECO:0000313|Proteomes:UP000253884};
RX PubMed=29574602; DOI=10.1007/s10295-018-2029-1;
RA Xu Y., Tan G., Ke M., Li J., Tang Y., Meng S., Niu J., Wang Y., Liu R.,
RA Wu H., Bai L., Zhang L., Zhang B.;
RT "Enhanced lincomycin production by co-overexpression of metK1 and metK2 in
RT Streptomyces lincolnensis.";
RL J. Ind. Microbiol. Biotechnol. 45:345-355(2018).
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DR EMBL; CP016438; ANS63760.1; -; Genomic_DNA.
DR EMBL; CP022744; AXG52683.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B1M537; -.
DR STRING; 1915.SLINC_1536; -.
DR KEGG; sls:SLINC_1536; -.
DR PATRIC; fig|1915.4.peg.1744; -.
DR Proteomes; UP000092598; Chromosome.
DR Proteomes; UP000253884; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.10.3730.20; -; 1.
DR InterPro; IPR000620; EamA_dom.
DR PANTHER; PTHR42920:SF28; EAMA DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42920; OS03G0707200 PROTEIN-RELATED; 1.
DR Pfam; PF00892; EamA; 2.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092598};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 66..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 65..195
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
FT DOMAIN 207..352
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 358..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 382 AA; 39219 MW; 551DF0F5F954FD2F CRC64;
MSRRSEHPRA IDPNTRALSI RTPAPRRSGP LGETGVMRDD AHVVACHHVP VHTSESIQSH
RNRGTGLSLA LVSALAFGGS GVAAKPLIEA GLDPLHVVWL RVAGAALVML PLAVRHRGLL
RSRPGLLLGF GLLAVAGVQA CYFAAISRIP VGVALLVEYL GPALVLGWVR FVQRRSVTRA
AALGVVLAVG GLACVVEVWS GLSFDALGLL LALGAACCQA GYFVLSDQGG DSGDQAPDPL
GVIAYGFLVG TVVLTVVARP WRLDWSVLGR AADMDGTAVS GGLLLAWIVF VATVLAYVTG
VHSVRRLSPQ VAGVVACLEA VVATVLAWIL LGEHLSAPQI VGGAIVLAGA FIAQSSAPAK
GSADPVASGG AETELSAREN AA
//
