ID A0A1B1M6P8_STRLN Unreviewed; 335 AA.
AC A0A1B1M6P8;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Membrane protein {ECO:0000313|EMBL:ANS64315.1};
GN ORFNames=GJU35_11050 {ECO:0000313|EMBL:QMV06138.1}, SLCG_6321
GN {ECO:0000313|EMBL:AXG57476.1}, SLINC_2091
GN {ECO:0000313|EMBL:ANS64315.1};
OS Streptomyces lincolnensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1915 {ECO:0000313|EMBL:ANS64315.1, ECO:0000313|Proteomes:UP000092598};
RN [1] {ECO:0000313|EMBL:ANS64315.1, ECO:0000313|Proteomes:UP000092598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2936 {ECO:0000313|EMBL:ANS64315.1,
RC ECO:0000313|Proteomes:UP000092598};
RA Meng S.C.;
RT "Enhancement of antibiotic productionsby engineered nitrateutilization in
RT actinobacteria.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AXG57476.1, ECO:0000313|Proteomes:UP000253884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LC-G {ECO:0000313|EMBL:AXG57476.1,
RC ECO:0000313|Proteomes:UP000253884};
RX PubMed=29574602; DOI=10.1007/s10295-018-2029-1;
RA Xu Y., Tan G., Ke M., Li J., Tang Y., Meng S., Niu J., Wang Y., Liu R.,
RA Wu H., Bai L., Zhang L., Zhang B.;
RT "Enhanced lincomycin production by co-overexpression of metK1 and metK2 in
RT Streptomyces lincolnensis.";
RL J. Ind. Microbiol. Biotechnol. 45:345-355(2018).
RN [3] {ECO:0000313|EMBL:QMV06138.1, ECO:0000313|Proteomes:UP000515335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B48 {ECO:0000313|EMBL:QMV06138.1,
RC ECO:0000313|Proteomes:UP000515335};
RX PubMed=32322696;
RA Wang R., Kong F., Wu H., Hou B., Kang Y., Cao Y., Duan S., Ye J., Zhang H.;
RT "Complete genome sequence of high-yield strain S. lincolnensis B48 and
RT identification of crucial mutations contributing to lincomycin
RT overproduction.";
RL Synth Syst Biotechnol 5:37-48(2020).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP016438; ANS64315.1; -; Genomic_DNA.
DR EMBL; CP022744; AXG57476.1; -; Genomic_DNA.
DR EMBL; CP046024; QMV06138.1; -; Genomic_DNA.
DR RefSeq; WP_067430103.1; NZ_CP046024.1.
DR AlphaFoldDB; A0A1B1M6P8; -.
DR STRING; 1915.SLINC_2091; -.
DR KEGG; sls:SLINC_2091; -.
DR PATRIC; fig|1915.4.peg.2332; -.
DR OrthoDB; 4270482at2; -.
DR Proteomes; UP000092598; Chromosome.
DR Proteomes; UP000253884; Chromosome.
DR Proteomes; UP000515335; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006825; P:copper ion transport; IEA:InterPro.
DR InterPro; IPR032694; CopC/D.
DR InterPro; IPR008457; Cu-R_CopD_dom.
DR PANTHER; PTHR34820; INNER MEMBRANE PROTEIN YEBZ; 1.
DR PANTHER; PTHR34820:SF4; INNER MEMBRANE PROTEIN YEBZ; 1.
DR Pfam; PF05425; CopD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092598};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 229..326
FT /note="Copper resistance protein D"
FT /evidence="ECO:0000259|Pfam:PF05425"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 335 AA; 34051 MW; CCABF00BB81E992E CRC64;
MTLIRPGPGV AEASGPERRP GAGRAVAVLV LVALGASIPL LGPSVALHDT GEAAAPGVRG
VGLLRTVLFA ALCVPLGELF VHRLARAVPG APPATPRSWA PYAAGTGFVA ALGLASVVAT
GNLVPGAVAE IDVGGLYASR EGKLALIEVN AFLAAGLCAL SRRPATQVWP LAAVLVAEAL
RAHPAPEDTA LVGSGLTLVH LACASLWTGG LLYALRTLRH WRSAAVGAAL LGLYARVAAV
LLAVITATGV WSSLRRMPSH TILEQLTTTA YGRALLAKVL LVAAVAALAL WARIRLGRAA
DPLTACSPAR AEVVVLGTVV ALSGLLTALP LPIRW
//
