ID A0A1B1M7U7_STRLN Unreviewed; 420 AA.
AC A0A1B1M7U7;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=L,D-transpeptidase family protein {ECO:0000313|EMBL:QMV06515.1};
DE SubName: Full=Lipoprotein {ECO:0000313|EMBL:ANS64708.1};
GN ORFNames=GJU35_13075 {ECO:0000313|EMBL:QMV06515.1}, SLCG_5930
GN {ECO:0000313|EMBL:AXG57085.1}, SLINC_2484
GN {ECO:0000313|EMBL:ANS64708.1};
OS Streptomyces lincolnensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1915 {ECO:0000313|EMBL:ANS64708.1, ECO:0000313|Proteomes:UP000092598};
RN [1] {ECO:0000313|EMBL:ANS64708.1, ECO:0000313|Proteomes:UP000092598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2936 {ECO:0000313|EMBL:ANS64708.1,
RC ECO:0000313|Proteomes:UP000092598};
RA Meng S.C.;
RT "Enhancement of antibiotic productionsby engineered nitrateutilization in
RT actinobacteria.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AXG57085.1, ECO:0000313|Proteomes:UP000253884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LC-G {ECO:0000313|EMBL:AXG57085.1,
RC ECO:0000313|Proteomes:UP000253884};
RX PubMed=29574602; DOI=10.1007/s10295-018-2029-1;
RA Xu Y., Tan G., Ke M., Li J., Tang Y., Meng S., Niu J., Wang Y., Liu R.,
RA Wu H., Bai L., Zhang L., Zhang B.;
RT "Enhanced lincomycin production by co-overexpression of metK1 and metK2 in
RT Streptomyces lincolnensis.";
RL J. Ind. Microbiol. Biotechnol. 45:345-355(2018).
RN [3] {ECO:0000313|EMBL:QMV06515.1, ECO:0000313|Proteomes:UP000515335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B48 {ECO:0000313|EMBL:QMV06515.1,
RC ECO:0000313|Proteomes:UP000515335};
RX PubMed=32322696;
RA Wang R., Kong F., Wu H., Hou B., Kang Y., Cao Y., Duan S., Ye J., Zhang H.;
RT "Complete genome sequence of high-yield strain S. lincolnensis B48 and
RT identification of crucial mutations contributing to lincomycin
RT overproduction.";
RL Synth Syst Biotechnol 5:37-48(2020).
CC -!- PATHWAY: Cell wall biogenesis; peptidoglycan biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004752}.
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DR EMBL; CP016438; ANS64708.1; -; Genomic_DNA.
DR EMBL; CP022744; AXG57085.1; -; Genomic_DNA.
DR EMBL; CP046024; QMV06515.1; -; Genomic_DNA.
DR RefSeq; WP_067431174.1; NZ_CP046024.1.
DR AlphaFoldDB; A0A1B1M7U7; -.
DR STRING; 1915.SLINC_2484; -.
DR KEGG; sls:SLINC_2484; -.
DR PATRIC; fig|1915.4.peg.2750; -.
DR OrthoDB; 5242354at2; -.
DR UniPathway; UPA00219; -.
DR Proteomes; UP000092598; Chromosome.
DR Proteomes; UP000253884; Chromosome.
DR Proteomes; UP000515335; Chromosome.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd16913; YkuD_like; 1.
DR Gene3D; 2.60.40.3710; -; 1.
DR Gene3D; 2.60.40.3780; -; 1.
DR Gene3D; 2.40.440.10; L,D-transpeptidase catalytic domain-like; 1.
DR InterPro; IPR041280; Big_10.
DR InterPro; IPR005490; LD_TPept_cat_dom.
DR InterPro; IPR038063; Transpep_catalytic_dom.
DR PANTHER; PTHR30582; L,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30582:SF35; L,D-TRANSPEPTIDASE 2; 1.
DR Pfam; PF17964; Big_10; 1.
DR Pfam; PF03734; YkuD; 1.
DR SUPFAM; SSF141523; L,D-transpeptidase catalytic domain-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Lipoprotein {ECO:0000313|EMBL:ANS64708.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000092598};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..420
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5038294404"
FT DOMAIN 56..222
FT /note="Bacterial Ig"
FT /evidence="ECO:0000259|Pfam:PF17964"
FT DOMAIN 245..368
FT /note="L,D-transpeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF03734"
FT REGION 400..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 420 AA; 45177 MW; 794507A709445CCA CRC64;
MSHAPRTRTV VGCTLLVIAL GAGVTACGSD GHPLSAEPYD AADQIAFTGP VGDGKKTDPD
KPLEVTAEDD DGRITDVTAQ DATGRHVAGE LSADGSRWHS TSPLAANAHY TVRVSTEDED
GAPGRRVVTF DTGKPRTKKR LDVTFGPKAG KYGVGQPVTA ELSMPVKDRA QRAVVERALK
VESTPAVQGA WHWVDDKELH YRPKEYWPTR ATVQVRSNLE GIKISDRLWG GRAKPLRLTT
GDRVIAVTDA SSHSMTVYRN GEAINTIPVT TGKAGFETRN GVKVVLGKEY FVRMRGTSIG
IAEGSSESYD LPVYYATRVT WSGEYVHAAP WSVGSQGYAN VSHGCTGMST ADAEWFFDTV
REGDLVKVVN SYGNTMEPFG NGFGDWNLAW KKWRGGSALV AGDPEGPGPE EAARLRPTAV
//
