ID A0A1B1M9G3_STRLN Unreviewed; 258 AA.
AC A0A1B1M9G3;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=SAM-dependent methyltransferase {ECO:0000313|EMBL:QMV07041.1};
GN ORFNames=GJU35_16045 {ECO:0000313|EMBL:QMV07041.1}, SLCG_5368
GN {ECO:0000313|EMBL:AXG56523.1}, SLINC_3045
GN {ECO:0000313|EMBL:ANS65269.1};
OS Streptomyces lincolnensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1915 {ECO:0000313|EMBL:ANS65269.1, ECO:0000313|Proteomes:UP000092598};
RN [1] {ECO:0000313|EMBL:ANS65269.1, ECO:0000313|Proteomes:UP000092598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2936 {ECO:0000313|EMBL:ANS65269.1,
RC ECO:0000313|Proteomes:UP000092598};
RA Meng S.C.;
RT "Enhancement of antibiotic productionsby engineered nitrateutilization in
RT actinobacteria.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AXG56523.1, ECO:0000313|Proteomes:UP000253884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LC-G {ECO:0000313|EMBL:AXG56523.1,
RC ECO:0000313|Proteomes:UP000253884};
RX PubMed=29574602; DOI=10.1007/s10295-018-2029-1;
RA Xu Y., Tan G., Ke M., Li J., Tang Y., Meng S., Niu J., Wang Y., Liu R.,
RA Wu H., Bai L., Zhang L., Zhang B.;
RT "Enhanced lincomycin production by co-overexpression of metK1 and metK2 in
RT Streptomyces lincolnensis.";
RL J. Ind. Microbiol. Biotechnol. 45:345-355(2018).
RN [3] {ECO:0000313|EMBL:QMV07041.1, ECO:0000313|Proteomes:UP000515335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B48 {ECO:0000313|EMBL:QMV07041.1,
RC ECO:0000313|Proteomes:UP000515335};
RX PubMed=32322696;
RA Wang R., Kong F., Wu H., Hou B., Kang Y., Cao Y., Duan S., Ye J., Zhang H.;
RT "Complete genome sequence of high-yield strain S. lincolnensis B48 and
RT identification of crucial mutations contributing to lincomycin
RT overproduction.";
RL Synth Syst Biotechnol 5:37-48(2020).
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DR EMBL; CP016438; ANS65269.1; -; Genomic_DNA.
DR EMBL; CP022744; AXG56523.1; -; Genomic_DNA.
DR EMBL; CP046024; QMV07041.1; -; Genomic_DNA.
DR RefSeq; WP_067432716.1; NZ_CP046024.1.
DR AlphaFoldDB; A0A1B1M9G3; -.
DR STRING; 1915.SLINC_3045; -.
DR KEGG; sls:SLINC_3045; -.
DR PATRIC; fig|1915.4.peg.3349; -.
DR OrthoDB; 4134439at2; -.
DR Proteomes; UP000092598; Chromosome.
DR Proteomes; UP000253884; Chromosome.
DR Proteomes; UP000515335; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR006764; SAM_dep_MeTrfase_SAV2177_type.
DR Pfam; PF04672; Methyltransf_19; 1.
DR PIRSF; PIRSF017393; MTase_SAV2177; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:QMV07041.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000092598};
KW Transferase {ECO:0000313|EMBL:QMV07041.1}.
FT REGION 238..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 258 AA; 27914 MW; 7769BE66AD63DB48 CRC64;
MTEIDTSVPH SARIWNYWLG GKDNYPVDEL AGDAYTAVFP GISTIARSSR AFLGRSIRYL
VQEAGVRQFL DVGTGLPTVD NTHEVAQRHA PESRIVYVDN DPLVLAHARA LLTSTPEGAT
AYEDISLSEP ERILQAAGRT LDLTRPTALI LSGILGHVDG HDRALDLVRR LLAGLPSGSY
LSVNDGSRGT DPDYEQAQDA YNETGAVPYF LRPVDQIEAY FEGLELVAPG VVPVPLWHPE
PGTDPSPVGQ HGGLGRKP
//
