ID A0A1B1MJQ0_STRLN Unreviewed; 301 AA.
AC A0A1B1MJQ0;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=ABC transporter permease subunit {ECO:0000313|EMBL:QMV10448.1};
DE SubName: Full=Binding-protein-dependent transport permease {ECO:0000313|EMBL:ANS68846.1};
GN ORFNames=GJU35_35495 {ECO:0000313|EMBL:QMV10448.1}, SLCG_1793
GN {ECO:0000313|EMBL:AXG52948.1}, SLINC_6622
GN {ECO:0000313|EMBL:ANS68846.1};
OS Streptomyces lincolnensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1915 {ECO:0000313|EMBL:ANS68846.1, ECO:0000313|Proteomes:UP000092598};
RN [1] {ECO:0000313|EMBL:ANS68846.1, ECO:0000313|Proteomes:UP000092598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2936 {ECO:0000313|EMBL:ANS68846.1,
RC ECO:0000313|Proteomes:UP000092598};
RA Meng S.C.;
RT "Enhancement of antibiotic productionsby engineered nitrateutilization in
RT actinobacteria.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AXG52948.1, ECO:0000313|Proteomes:UP000253884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LC-G {ECO:0000313|EMBL:AXG52948.1,
RC ECO:0000313|Proteomes:UP000253884};
RX PubMed=29574602; DOI=10.1007/s10295-018-2029-1;
RA Xu Y., Tan G., Ke M., Li J., Tang Y., Meng S., Niu J., Wang Y., Liu R.,
RA Wu H., Bai L., Zhang L., Zhang B.;
RT "Enhanced lincomycin production by co-overexpression of metK1 and metK2 in
RT Streptomyces lincolnensis.";
RL J. Ind. Microbiol. Biotechnol. 45:345-355(2018).
RN [3] {ECO:0000313|EMBL:QMV10448.1, ECO:0000313|Proteomes:UP000515335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B48 {ECO:0000313|EMBL:QMV10448.1,
RC ECO:0000313|Proteomes:UP000515335};
RX PubMed=32322696;
RA Wang R., Kong F., Wu H., Hou B., Kang Y., Cao Y., Duan S., Ye J., Zhang H.;
RT "Complete genome sequence of high-yield strain S. lincolnensis B48 and
RT identification of crucial mutations contributing to lincomycin
RT overproduction.";
RL Synth Syst Biotechnol 5:37-48(2020).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC ECO:0000256|RuleBase:RU363032}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363032}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. {ECO:0000256|RuleBase:RU363032}.
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DR EMBL; CP016438; ANS68846.1; -; Genomic_DNA.
DR EMBL; CP022744; AXG52948.1; -; Genomic_DNA.
DR EMBL; CP046024; QMV10448.1; -; Genomic_DNA.
DR RefSeq; WP_067442040.1; NZ_CP046024.1.
DR AlphaFoldDB; A0A1B1MJQ0; -.
DR STRING; 1915.SLINC_6622; -.
DR KEGG; sls:SLINC_6622; -.
DR PATRIC; fig|1915.4.peg.7311; -.
DR OrthoDB; 2063054at2; -.
DR Proteomes; UP000092598; Chromosome.
DR Proteomes; UP000253884; Chromosome.
DR Proteomes; UP000515335; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; MetI-like; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR PANTHER; PTHR43744:SF12; ABC TRANSPORTER PERMEASE PROTEIN MG189-RELATED; 1.
DR PANTHER; PTHR43744; ABC TRANSPORTER PERMEASE PROTEIN MG189-RELATED-RELATED; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; MetI-like; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363032};
KW Reference proteome {ECO:0000313|Proteomes:UP000092598};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363032};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363032}; Transport {ECO:0000256|RuleBase:RU363032}.
FT TRANSMEM 31..51
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 97..116
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 128..150
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 162..181
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 202..226
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 265..287
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT DOMAIN 93..286
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50928"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 301 AA; 33449 MW; A045ECD88CE19605 CRC64;
MTLTEDRAKS SQVRRLSAPD PVSRTRGSQR FLLVGLSLAS VYSLFPVWWL IVAATKDRTG
LYQSNGLWFS GWHLWDNLRQ LFTYEDGIFL RWTANSFLYA GVGSLGGTLL ALATGYGLAR
FDFPGRNVVF AAVVGSFLIP IALLTLPLYL LFSDIGLVDT PWAMLIPCLI NPFSVYLAKV
YTEATIPFEL LEAARIDGAG ELRIFFSIVL RMMTTGGATV FLLAFVNTWN AFFLPLTVLR
GEENWTLNLG LYNWSGKRLE SGVDLTSLVL TGALLSIVPM AIMMVAMRRY WRSGVTMGAL
K
//
