ID A0A1B1MKT4_STRLN Unreviewed; 497 AA.
AC A0A1B1MKT4;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Phosphatase PAP2 family protein {ECO:0000313|EMBL:QMV10737.1};
GN ORFNames=GJU35_37080 {ECO:0000313|EMBL:QMV10737.1}, SLCG_6917
GN {ECO:0000313|EMBL:AXG58072.1}, SLINC_6929
GN {ECO:0000313|EMBL:ANS69153.1};
OS Streptomyces lincolnensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1915 {ECO:0000313|EMBL:ANS69153.1, ECO:0000313|Proteomes:UP000092598};
RN [1] {ECO:0000313|EMBL:ANS69153.1, ECO:0000313|Proteomes:UP000092598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2936 {ECO:0000313|EMBL:ANS69153.1,
RC ECO:0000313|Proteomes:UP000092598};
RA Meng S.C.;
RT "Enhancement of antibiotic productionsby engineered nitrateutilization in
RT actinobacteria.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AXG58072.1, ECO:0000313|Proteomes:UP000253884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LC-G {ECO:0000313|EMBL:AXG58072.1,
RC ECO:0000313|Proteomes:UP000253884};
RX PubMed=29574602; DOI=10.1007/s10295-018-2029-1;
RA Xu Y., Tan G., Ke M., Li J., Tang Y., Meng S., Niu J., Wang Y., Liu R.,
RA Wu H., Bai L., Zhang L., Zhang B.;
RT "Enhanced lincomycin production by co-overexpression of metK1 and metK2 in
RT Streptomyces lincolnensis.";
RL J. Ind. Microbiol. Biotechnol. 45:345-355(2018).
RN [3] {ECO:0000313|EMBL:QMV10737.1, ECO:0000313|Proteomes:UP000515335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B48 {ECO:0000313|EMBL:QMV10737.1,
RC ECO:0000313|Proteomes:UP000515335};
RX PubMed=32322696;
RA Wang R., Kong F., Wu H., Hou B., Kang Y., Cao Y., Duan S., Ye J., Zhang H.;
RT "Complete genome sequence of high-yield strain S. lincolnensis B48 and
RT identification of crucial mutations contributing to lincomycin
RT overproduction.";
RL Synth Syst Biotechnol 5:37-48(2020).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP016438; ANS69153.1; -; Genomic_DNA.
DR EMBL; CP022744; AXG58072.1; -; Genomic_DNA.
DR EMBL; CP046024; QMV10737.1; -; Genomic_DNA.
DR RefSeq; WP_067442642.1; NZ_CP046024.1.
DR AlphaFoldDB; A0A1B1MKT4; -.
DR STRING; 1915.SLINC_6929; -.
DR KEGG; sls:SLINC_6929; -.
DR PATRIC; fig|1915.4.peg.7637; -.
DR OrthoDB; 5242960at2; -.
DR Proteomes; UP000092598; Chromosome.
DR Proteomes; UP000253884; Chromosome.
DR Proteomes; UP000515335; Chromosome.
DR GO; GO:0016301; F:kinase activity; IEA:InterPro.
DR CDD; cd01610; PAP2_like; 1.
DR Gene3D; 2.60.200.40; -; 1.
DR Gene3D; 1.20.144.10; Phosphatidic acid phosphatase type 2/haloperoxidase; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR InterPro; IPR036938; P_Acid_Pase_2/haloperoxi_sf.
DR InterPro; IPR000326; P_Acid_Pase_2/haloperoxidase.
DR PANTHER; PTHR14969:SF13; AT30094P; 1.
DR PANTHER; PTHR14969; SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR Pfam; PF01569; PAP2; 1.
DR SMART; SM00014; acidPPc; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF48317; Acid phosphatase/Vanadium-dependent haloperoxidase; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000092598}.
FT DOMAIN 249..329
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
SQ SEQUENCE 497 AA; 52397 MW; 8295A0EED65C3B55 CRC64;
MSPDVDLTVP KPGHHVLREK LLALDSRLFE FAAEQHWPAA EPVLPRLSRS ANHGVLWFAT
AAAMAASRTP RARRAAARGL ASLGLASLTI NTIGKRSVRR TRPVLDPVPL VRQLKRQPIT
TSFPSGHSAS AAAFATGVAL ESPSWGAVVA PVAFSVAMSR VYTGVHFPSD VLAGAALGAG
AAFVVRRLVP TRAQVVPPAR PRAEVPALAD GEGLVMVSNT ASGTADRVRA LRDILPAAEV
VECEPADVRA ELEKAAARAR VLGVCGGDGT VNAAAEIALR HGLPLAVLPG GTLNHFAYDL
GVEGVRDLGR AVQQGEGVHV DVGRFACGET QGVFLNTLSL GVYPELVRER ERWTRRIGGW
PAGVIAALRV VRADRHPLEA EFRGRARPLW LLFVGNGTYH RMGLGPGRRS DLADGQLDVR
VVHGGRRPAA RLLAAALAGP LTRSPVHAAV QVGRLNVASV APGTLLAYDG EVIEVEGSVT
LEKLPQALTV YRPSTGS
//
