ID A0A1B1MN74_STRLN Unreviewed; 490 AA.
AC A0A1B1MN74;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Amino acid permease {ECO:0000313|EMBL:QMV11562.1};
DE SubName: Full=Putative amino acid transporter transmembrane protein s {ECO:0000313|EMBL:ANS70061.1};
GN ORFNames=GJU35_41720 {ECO:0000313|EMBL:QMV11562.1}, SLCG_7803
GN {ECO:0000313|EMBL:AXG58958.1}, SLINC_7837
GN {ECO:0000313|EMBL:ANS70061.1};
OS Streptomyces lincolnensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1915 {ECO:0000313|EMBL:ANS70061.1, ECO:0000313|Proteomes:UP000092598};
RN [1] {ECO:0000313|EMBL:ANS70061.1, ECO:0000313|Proteomes:UP000092598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2936 {ECO:0000313|EMBL:ANS70061.1,
RC ECO:0000313|Proteomes:UP000092598};
RA Meng S.C.;
RT "Enhancement of antibiotic productionsby engineered nitrateutilization in
RT actinobacteria.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AXG58958.1, ECO:0000313|Proteomes:UP000253884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LC-G {ECO:0000313|EMBL:AXG58958.1,
RC ECO:0000313|Proteomes:UP000253884};
RX PubMed=29574602; DOI=10.1007/s10295-018-2029-1;
RA Xu Y., Tan G., Ke M., Li J., Tang Y., Meng S., Niu J., Wang Y., Liu R.,
RA Wu H., Bai L., Zhang L., Zhang B.;
RT "Enhanced lincomycin production by co-overexpression of metK1 and metK2 in
RT Streptomyces lincolnensis.";
RL J. Ind. Microbiol. Biotechnol. 45:345-355(2018).
RN [3] {ECO:0000313|EMBL:QMV11562.1, ECO:0000313|Proteomes:UP000515335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B48 {ECO:0000313|EMBL:QMV11562.1,
RC ECO:0000313|Proteomes:UP000515335};
RX PubMed=32322696;
RA Wang R., Kong F., Wu H., Hou B., Kang Y., Cao Y., Duan S., Ye J., Zhang H.;
RT "Complete genome sequence of high-yield strain S. lincolnensis B48 and
RT identification of crucial mutations contributing to lincomycin
RT overproduction.";
RL Synth Syst Biotechnol 5:37-48(2020).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP016438; ANS70061.1; -; Genomic_DNA.
DR EMBL; CP022744; AXG58958.1; -; Genomic_DNA.
DR EMBL; CP046024; QMV11562.1; -; Genomic_DNA.
DR RefSeq; WP_067443567.1; NZ_CP046024.1.
DR AlphaFoldDB; A0A1B1MN74; -.
DR STRING; 1915.SLINC_7837; -.
DR KEGG; sls:SLINC_7837; -.
DR PATRIC; fig|1915.4.peg.8619; -.
DR OrthoDB; 138827at2; -.
DR Proteomes; UP000092598; Chromosome.
DR Proteomes; UP000253884; Chromosome.
DR Proteomes; UP000515335; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR002293; AA/rel_permease1.
DR PANTHER; PTHR42770; AMINO ACID TRANSPORTER-RELATED; 1.
DR PANTHER; PTHR42770:SF12; AMINO ACID TRANSPORTER-RELATED; 1.
DR Pfam; PF13520; AA_permease_2; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092598};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 425..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 490 AA; 52067 MW; 3825D20F651EC46A CRC64;
MSINRGRGLQ ANALGTFDTV VMAVAGSAPA YSLAATTAVL VGAVGLASPA ALLYCAIPML
GIALAFSYLG RIDVNAGASY SWVGRTLHPF LGFMSGWALV ISTTIFMVAG SLPAGSMTLS
LFDEQLAENT ALSTAVGAGW FLIMLLVVLG GARLTVRAQF LMSGIELAIL ALFAVLAVFH
TDNARAFDWS WLGFGHFDGM AGFASGALIA AFYYWGWDVT SNLSEETRNS RRTTGLAGLI
GVGIVFLLFE AFTIAVNMIL SAKQIEENDA NVLAVLGEEI WPGWGGKLLV VAVMLSTIAT
LETTLIQVTR SLFAMGRDRT MPSALGRVHP HWNTPWVAIT VVGTVAMVML VASNALGTVG
DILSDAISAI GLQIAVYYGL AGLAAVVAYR RMLLKSVANF VLGGLWPLFG SLFMFWVLVE
SLGELSTASV TIGLGGLAVG LIPMFWYWMR GSDYYRPARL DAARTIETEY VPDDGALAHS
RAHEGFPTDF
//
