ID A0A1B1NDT5_9MICO Unreviewed; 177 AA.
AC A0A1B1NDT5;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase {ECO:0000256|ARBA:ARBA00012257};
DE EC=4.1.1.97 {ECO:0000256|ARBA:ARBA00012257};
GN ORFNames=SGUI_2188 {ECO:0000313|EMBL:ANS79584.1};
OS Serinicoccus hydrothermalis.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC Ornithinimicrobiaceae; Serinicoccus.
OX NCBI_TaxID=1758689 {ECO:0000313|EMBL:ANS79584.1, ECO:0000313|Proteomes:UP000092482};
RN [1] {ECO:0000313|EMBL:ANS79584.1, ECO:0000313|Proteomes:UP000092482}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JLT9 {ECO:0000313|EMBL:ANS79584.1,
RC ECO:0000313|Proteomes:UP000092482};
RA Tang K.;
RT "Shallow-sea hydrothermal system.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-
CC carboxylate + H(+) = (S)-allantoin + CO2; Xref=Rhea:RHEA:26301,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:15678, ChEBI:CHEBI:16526,
CC ChEBI:CHEBI:58639; EC=4.1.1.97;
CC Evidence={ECO:0000256|ARBA:ARBA00001163};
CC -!- PATHWAY: Purine metabolism; urate degradation; (S)-allantoin from
CC urate: step 3/3. {ECO:0000256|ARBA:ARBA00004754}.
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DR EMBL; CP014989; ANS79584.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B1NDT5; -.
DR STRING; 1758689.SGUI_2188; -.
DR KEGG; serj:SGUI_2188; -.
DR OrthoDB; 5243781at2; -.
DR Proteomes; UP000092482; Chromosome.
DR GO; GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0006144; P:purine nucleobase metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.3330.10; Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; 1.
DR InterPro; IPR018020; OHCU_decarboxylase.
DR InterPro; IPR017595; OHCU_decarboxylase-2.
DR InterPro; IPR036778; OHCU_decarboxylase_sf.
DR NCBIfam; TIGR03180; UraD_2; 1.
DR PANTHER; PTHR43466; 2-OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE-RELATED; 1.
DR PANTHER; PTHR43466:SF1; 2-OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE-RELATED; 1.
DR Pfam; PF09349; OHCU_decarbox; 1.
DR SUPFAM; SSF158694; UraD-Like; 1.
PE 4: Predicted;
KW Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Purine metabolism {ECO:0000256|ARBA:ARBA00022631};
KW Reference proteome {ECO:0000313|Proteomes:UP000092482}.
FT DOMAIN 20..172
FT /note="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline
FT decarboxylase"
FT /evidence="ECO:0000259|Pfam:PF09349"
FT REGION 79..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 177 AA; 19444 MW; 9A0F88F8BD3E1D9B CRC64;
MAQQPSDETD DALDLTAWQA LGPHAARETL LSCCSSPRWA DAVVQGRPYA GVEELLEASD
DAFGSLTAED VADALAGHPR IGERASGSGR DARFSQSEQS AVAGSAQDVQ DRLRAGNQAY
EQRFDRVFLI RAAGRGPEEI LTELERRLTN DDETETAEVV EQLRQITRRR LQELIHP
//
