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Database: UniProt
Entry: A0A1B1Q4Z2_9CHLB
LinkDB: A0A1B1Q4Z2_9CHLB
Original site: A0A1B1Q4Z2_9CHLB 
ID   A0A1B1Q4Z2_9CHLB        Unreviewed;       273 AA.
AC   A0A1B1Q4Z2;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   11-DEC-2019, entry version 12.
DE   RecName: Full=2-dehydro-3-deoxyphosphooctonate aldolase {ECO:0000256|SAAS:SAAS00700405};
DE            EC=2.5.1.55 {ECO:0000256|SAAS:SAAS00700404};
GN   Name=kdsA {ECO:0000313|EMBL:ANT65914.1};
GN   ORFNames=Ptc2401_02185 {ECO:0000313|EMBL:ANT65914.1};
OS   Prosthecochloris sp. CIB 2401.
OC   Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae;
OC   Prosthecochloris; unclassified Prosthecochloris.
OX   NCBI_TaxID=1868325 {ECO:0000313|EMBL:ANT65914.1, ECO:0000313|Proteomes:UP000092496};
RN   [1] {ECO:0000313|EMBL:ANT65914.1, ECO:0000313|Proteomes:UP000092496}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIB 2401 {ECO:0000313|EMBL:ANT65914.1,
RC   ECO:0000313|Proteomes:UP000092496};
RA   Nabhan S., Bunk B., Sproeer C., Bryant D.A., Overmann J.;
RT   "Genome Sequence of Prosthecochloris phaeum CIB2401 of the phylum
RT   Chlorobi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-deoxy-
CC         alpha-D-manno-2-octulosonate-8-phosphate + phosphate;
CC         Xref=Rhea:RHEA:14053, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:57693, ChEBI:CHEBI:58702, ChEBI:CHEBI:85985; EC=2.5.1.55;
CC         Evidence={ECO:0000256|SAAS:SAAS01123735};
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; lipopolysaccharide
CC       biosynthesis. {ECO:0000256|SAAS:SAAS00700395}.
CC   -!- PATHWAY: Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate
CC       biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate:
CC       step 2/3. {ECO:0000256|SAAS:SAAS00700401}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00700398}.
CC   -!- SIMILARITY: Belongs to the KdsA family.
CC       {ECO:0000256|SAAS:SAAS00700400}.
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DR   EMBL; CP016432; ANT65914.1; -; Genomic_DNA.
DR   RefSeq; WP_068868041.1; NZ_CP016432.1.
DR   EnsemblBacteria; ANT65914; ANT65914; Ptc2401_02185.
DR   KEGG; proc:Ptc2401_02185; -.
DR   PATRIC; fig|1868325.3.peg.2151; -.
DR   KO; K01627; -.
DR   OrthoDB; 687380at2; -.
DR   UniPathway; UPA00030; -.
DR   UniPathway; UPA00357; UER00474.
DR   Proteomes; UP000092496; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008676; F:3-deoxy-8-phosphooctulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006269; KDO8P_synthase.
DR   PANTHER; PTHR21057; PTHR21057; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   TIGRFAMs; TIGR01362; KDO8P_synth; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00700397};
KW   Lipopolysaccharide biosynthesis {ECO:0000256|SAAS:SAAS00700406};
KW   Reference proteome {ECO:0000313|Proteomes:UP000092496};
KW   Transferase {ECO:0000256|SAAS:SAAS00080156, ECO:0000313|EMBL:ANT65914.1}.
FT   DOMAIN          8..271
FT                   /note="DAHP_synth_1"
FT                   /evidence="ECO:0000259|Pfam:PF00793"
SQ   SEQUENCE   273 AA;  29250 MW;  DDF4BF35A446E2AC CRC64;
     MEKFSIGGIR IPQDNGLFFI AGPCLIEGRD MAMEVAAELS GFARQTGVPV IFKGSFRKAN
     RSSKESFTGI GDTAALEILA EVRERYGMPV LTDVHNVQDV QLASGYVDVL QIPAFLCRQT
     ELLVAAGESG LAVNIKKGQF MAPEDMSLAA AKVADSGNER IMLTERGTSF GYHNLVVDFR
     GVPRMARSGY SVVYDATHSL QLPSAGNGVS SGEREFLRPL ARAAVAAGVD GIFAEVHPQP
     SRAHSDAATQ IPLGEFAGFA RELQQLKTCV QSL
//
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