ID A0A1B1ZWY5_9PSEU Unreviewed; 790 AA.
AC A0A1B1ZWY5;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=NADH dehydrogenase {ECO:0000313|EMBL:ANY10215.1};
GN ORFNames=AFB00_19865 {ECO:0000313|EMBL:ANY10215.1};
OS Pseudonocardia sp. HH130630-07.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Pseudonocardia.
OX NCBI_TaxID=1690815 {ECO:0000313|EMBL:ANY10215.1, ECO:0000313|Proteomes:UP000092926};
RN [1] {ECO:0000313|EMBL:ANY10215.1, ECO:0000313|Proteomes:UP000092926}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HH130630-07 {ECO:0000313|EMBL:ANY10215.1,
RC ECO:0000313|Proteomes:UP000092926};
RA Oliw E.H.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}.
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DR EMBL; CP013854; ANY10215.1; -; Genomic_DNA.
DR RefSeq; WP_068800478.1; NZ_CP013854.1.
DR AlphaFoldDB; A0A1B1ZWY5; -.
DR STRING; 1690815.AFB00_19865; -.
DR KEGG; phh:AFB00_19865; -.
DR Proteomes; UP000092926; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR025383; MrpA_C/MbhD.
DR InterPro; IPR046806; MrpA_C/MbhE.
DR InterPro; IPR001750; ND/Mrp_mem.
DR InterPro; IPR001516; Proton_antipo_N.
DR PANTHER; PTHR43373:SF1; ANTIPORTER SUBUNIT MNHA2-RELATED; 1.
DR PANTHER; PTHR43373; NA(+)/H(+) ANTIPORTER SUBUNIT; 1.
DR Pfam; PF13244; MbhD; 1.
DR Pfam; PF20501; MbhE; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR Pfam; PF00662; Proton_antipo_N; 1.
DR PRINTS; PR01434; NADHDHGNASE5.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092926};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000320};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 73..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 451..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 492..519
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 566..589
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 595..615
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 622..641
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 647..666
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 687..707
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 744..763
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 63..96
FT /note="NADH-Ubiquinone oxidoreductase (complex I) chain 5
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00662"
FT DOMAIN 124..401
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
FT DOMAIN 606..670
FT /note="MrpA C-terminal/MbhD"
FT /evidence="ECO:0000259|Pfam:PF13244"
FT DOMAIN 687..760
FT /note="MrpA C-terminal/MbhE"
FT /evidence="ECO:0000259|Pfam:PF20501"
SQ SEQUENCE 790 AA; 81864 MW; BDA87D505AD4B9D8 CRC64;
MLAVVAAHLV LALCLPGLAR YHRRLAFGAG AVLLAGTLVW AVVQAPAALG PGVTDSLEWA
PELGLRLSLR LDALALAMIV LVSGVGALIM VYAAWYFGPR SRDAARSAAL LVTFAGMMLG
LVLADDLLTL YVFWELTSLT SFLLVGQGGQ YRENRRAAVQ ALLVTVFGGL SMLLGIVLLG
QLAGTYSIPE ITAASTAGTL APDEPVLLAV SLVLILMGAL TKSAQLPFHP WLPYAMAAPT
PISAYLHAAS MVKAGVVLVA RLGPAFAVHA VWWVPVVGLG LATMLLGGWR ALRQTDLKRL
LAFGTVSQLG FLMVLFGAGS RVAALAGIAM LLAHGLFKAP LFMVVGAIDK ACGTRDLREL
CGLGRRRRGL AVLGTLAGLS MAGLPPMLGF VGKEAAYEAF LLEGGVRGWI VALGLLTGSL
LTVAYTARFL WGAFATKGTR PTGGDPVPLG LSLPAWLCAL TGLAAGFAAP LVQEIAAAYA
RPLPPLGDPY AAQYGLALWH GIGLALGFTL VAVVGGLLLH RYGSALTGQA KIPGISAQRG
YEAVVTGLER FAIALTGRLQ IGSLPVYLAC ILITLIVLPG PVLALTGALP ESQEPYHSIM
QVPVGLMVIV AALALTRARR RFTAVLLVGA VGYGIGGLFV IDGAPDLALA QFLVETLTLV
AFVFVLRRLP AHFDEPETER RVRLPKAAVA AVGGLLVAGT AVVLSGARVL PPATTDAFVA
GAPQAGATNL ISAILVDFRA LDTIGEITIL LICAAGTASL VLATRYDKKK GGTVVDSGSG
SPKHEQEVLG
//
