ID   A0A1B2HXD8_9PSEU        Unreviewed;       418 AA.
AC   A0A1B2HXD8;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=3-hydroxyacyl-CoA dehydrogenase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BBK82_47015 {ECO:0000313|EMBL:ANZ42355.1};
OS   Lentzea guizhouensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Lentzea.
OX   NCBI_TaxID=1586287 {ECO:0000313|EMBL:ANZ42355.1, ECO:0000313|Proteomes:UP000093053};
RN   [1] {ECO:0000313|EMBL:ANZ42355.1, ECO:0000313|Proteomes:UP000093053}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DHS C013 {ECO:0000313|EMBL:ANZ42355.1,
RC   ECO:0000313|Proteomes:UP000093053};
RA   Cao C.;
RT   "Complete genome sequence of the Lentzea guizhouensis DHS C013.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Lipid metabolism; butanoate metabolism.
CC       {ECO:0000256|ARBA:ARBA00005086}.
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DR   EMBL; CP016793; ANZ42355.1; -; Genomic_DNA.
DR   RefSeq; WP_065920685.1; NZ_CP016793.1.
DR   AlphaFoldDB; A0A1B2HXD8; -.
DR   STRING; 1586287.BBK82_47015; -.
DR   KEGG; led:BBK82_47015; -.
DR   Proteomes; UP000093053; Chromosome.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR   PANTHER; PTHR48075:SF5; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR   Pfam; PF00725; 3HCDH; 2.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000093053}.
FT   DOMAIN          21..113
FT                   /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00725"
FT   DOMAIN          138..315
FT                   /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF02737"
FT   DOMAIN          318..411
FT                   /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00725"
SQ   SEQUENCE   418 AA;  44414 MW;  0D420D9AB55FFE44 CRC64;
     MLRLAGTEVV SLGGRPAEAA TALLYACVNR TVNLAAAGYA TVEDLDTALR LGCGLKFGPL
     HLLDLIGLDT VRSALLRLHE QTGSASYVPS PLLDRMVEEG LLGRKVGRGF HRYDHRGEIV
     PPARTAISGG TPREIRRAGV VGSGTMGRGI AEILIAAGIP TTLIARSTHK ADEAADRIHA
     SLTRLVRKGR MSEQDRQDVL ARLTVATGYD ALADADIVVE AVAEDMRAKR AVLQGIDAAL
     KPGAIIATTT SSLSVTECAN ATGRPADVIG LHFFNPAPVM RLVEVVRTGH TADDVHATAH
     ALVRWLRKTP VDCGDRVGFI VNHVLFPYLN DAIRMLARTD VTVDEIDTAV VTAYHHPMGP
     FTLLDTIGLD VSLAILETLS AASPTGEPEP AEELRRLVAA GHLGTKTGSG FRLVDNGR
//