ID A0A1B3LN60_9PROT Unreviewed; 395 AA.
AC A0A1B3LN60;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Acetyl-CoA C-acyltransferase family protein {ECO:0000313|EMBL:AOF82292.1};
DE EC=2.3.1.16 {ECO:0000313|EMBL:AOF82292.1};
GN ORFNames=BSY238_2970 {ECO:0000313|EMBL:AOF82292.1};
OS Methyloversatilis sp. RAC08.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Sterolibacteriaceae; Methyloversatilis.
OX NCBI_TaxID=1842540 {ECO:0000313|EMBL:AOF82292.1, ECO:0000313|Proteomes:UP000094168};
RN [1] {ECO:0000313|Proteomes:UP000094168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RAC08 {ECO:0000313|Proteomes:UP000094168};
RA Florea S., Webb J.S., Jaromczyk J., Schardl C.L.;
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; CP016448; AOF82292.1; -; Genomic_DNA.
DR RefSeq; WP_069039801.1; NZ_CP016448.1.
DR AlphaFoldDB; A0A1B3LN60; -.
DR STRING; 1842540.BSY238_2970; -.
DR KEGG; metr:BSY238_2970; -.
DR PATRIC; fig|1842540.3.peg.3011; -.
DR OrthoDB; 6139495at2; -.
DR Proteomes; UP000094168; Chromosome.
DR GO; GO:0003988; F:acetyl-CoA C-acyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:AOF82292.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000094168};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:AOF82292.1}.
FT DOMAIN 7..263
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 273..394
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 92
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 351
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 381
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 395 AA; 40681 MW; FC77EC1567B79CF0 CRC64;
MADKREVVIV GAARTPIGAY GGSLKDFTAC DLGAHVVKAA FARAGVDAKE AQHLVFGNVI
HTEARDMYVS RVVALNAGMA QESCAMGVNR LCGSGFQAIV SAANAIQLGD AECAVGGGVE
TMSRGGYLMP AARWGARMND TKMIDMMVGA LTDPFETTHM GITAENIASQ FGFGREEQDA
FAVESHRRAA AATDAGHFKS QIAPLEVQTK KGTTVIDTDE HFRRDATVEG MAKLRPVFKK
DGSVTAGNAS GINDGAAAIV MMEAGAAARA GAKPLARLVS YAVAGVAPSI MGTGPIPAVK
LALARAGLKA SDLDVIESNE AFAVQAMCVT RELGLDPAKV NVNGGAVGLG HPVGATGAVL
TVKCLYELQR TGGRYGLITM CIGGGQGIAG IIERI
//
