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Database: UniProt
Entry: A0A1B3NRI1_9BRAD
LinkDB: A0A1B3NRI1_9BRAD
Original site: A0A1B3NRI1_9BRAD 
ID   A0A1B3NRI1_9BRAD        Unreviewed;       426 AA.
AC   A0A1B3NRI1;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   16-JAN-2019, entry version 13.
DE   RecName: Full=Phosphoribosylamine--glycine ligase {ECO:0000256|HAMAP-Rule:MF_00138};
DE            EC=6.3.4.13 {ECO:0000256|HAMAP-Rule:MF_00138};
DE   AltName: Full=GARS {ECO:0000256|HAMAP-Rule:MF_00138};
DE   AltName: Full=Glycinamide ribonucleotide synthetase {ECO:0000256|HAMAP-Rule:MF_00138};
DE   AltName: Full=Phosphoribosylglycinamide synthetase {ECO:0000256|HAMAP-Rule:MF_00138};
GN   Name=purD {ECO:0000256|HAMAP-Rule:MF_00138,
GN   ECO:0000313|EMBL:AOG07934.1};
GN   ORFNames=BSY19_1505 {ECO:0000313|EMBL:AOG07934.1};
OS   Bosea sp. RAC05.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bradyrhizobiaceae; Bosea.
OX   NCBI_TaxID=1842539 {ECO:0000313|EMBL:AOG07934.1, ECO:0000313|Proteomes:UP000094689};
RN   [1] {ECO:0000313|EMBL:AOG07934.1, ECO:0000313|Proteomes:UP000094689}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RAC05 {ECO:0000313|EMBL:AOG07934.1,
RC   ECO:0000313|Proteomes:UP000094689};
RA   Florea S., Webb J.S., Jaromczyk J., Schardl C.L.;
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=5-phospho-D-ribosylamine + ATP + glycine = ADP + H(+) +
CC         N(1)-(5-phospho-D-ribosyl)glycinamide + phosphate;
CC         Xref=Rhea:RHEA:17453, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:57305, ChEBI:CHEBI:58089,
CC         ChEBI:CHEBI:58457, ChEBI:CHEBI:456216; EC=6.3.4.13;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_00138};
CC   -!- PATHWAY: Purine metabolism; IMP biosynthesis via de novo pathway;
CC       N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-
CC       ribose 1-diphosphate: step 2/2. {ECO:0000256|HAMAP-Rule:MF_00138}.
CC   -!- SIMILARITY: Belongs to the GARS family. {ECO:0000256|HAMAP-
CC       Rule:MF_00138}.
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DR   EMBL; CP016464; AOG07934.1; -; Genomic_DNA.
DR   RefSeq; WP_069054214.1; NZ_CP016464.1.
DR   EnsemblBacteria; AOG07934; AOG07934; BSY19_1505.
DR   KEGG; bos:BSY19_1505; -.
DR   PATRIC; fig|1842539.3.peg.1534; -.
DR   KO; K01945; -.
DR   OrthoDB; 932854at2; -.
DR   UniPathway; UPA00074; UER00125.
DR   Proteomes; UP000094689; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0009113; P:purine nucleobase biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.30.1490.20; -; 1.
DR   Gene3D; 3.90.600.10; -; 1.
DR   HAMAP; MF_00138; GARS; 1.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR016185; PreATP-grasp_dom_sf.
DR   InterPro; IPR020561; PRibGlycinamid_synth_ATP-grasp.
DR   InterPro; IPR000115; PRibGlycinamide_synth.
DR   InterPro; IPR020560; PRibGlycinamide_synth_C-dom.
DR   InterPro; IPR037123; PRibGlycinamide_synth_C_sf.
DR   InterPro; IPR020559; PRibGlycinamide_synth_CS.
DR   InterPro; IPR020562; PRibGlycinamide_synth_N.
DR   InterPro; IPR011054; Rudment_hybrid_motif.
DR   Pfam; PF01071; GARS_A; 1.
DR   Pfam; PF02843; GARS_C; 1.
DR   Pfam; PF02844; GARS_N; 1.
DR   SMART; SM01210; GARS_C; 1.
DR   SUPFAM; SSF51246; SSF51246; 1.
DR   SUPFAM; SSF52440; SSF52440; 1.
DR   TIGRFAMs; TIGR00877; purD; 1.
DR   PROSITE; PS50975; ATP_GRASP; 1.
DR   PROSITE; PS00184; GARS; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW   Complete proteome {ECO:0000313|Proteomes:UP000094689};
KW   Ligase {ECO:0000256|HAMAP-Rule:MF_00138, ECO:0000313|EMBL:AOG07934.1};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW   Purine biosynthesis {ECO:0000256|HAMAP-Rule:MF_00138};
KW   Reference proteome {ECO:0000313|Proteomes:UP000094689}.
FT   DOMAIN      107    312       ATP-grasp. {ECO:0000259|PROSITE:PS50975}.
SQ   SEQUENCE   426 AA;  43947 MW;  139F50A2427E4804 CRC64;
     MKILLIGSGG REHALAWAIS ASPLCDRLFI APGNPGTAQC GENVVLDIAD HGAVASFCKL
     QGIGLVVVGP EGPLVAGLAD DLVAAGLKVF GPSKTAAQLE GSKAFTKELC AEFGIPTAGF
     GRFADAASAK AYVAAKGAPI VIKADGLAAG KGVVMAETLD QANEAIDMMF GGGLGAAGAE
     VVIEEWMIGE EASFFALCDG TNALPLASAQ DHKRVGDGDT GPNTGGMGAY SPAPIMTPAM
     EARVMKEIVA PTLAGMAQRG TPFQGVLFAG LMITAQGPKL IEYNVRFGDP ECEVLMPRLR
     SDIVPALLAA CDGVLDNITL RWSDEAALTV VLAARGYPGK PETGSVIRDI DKAAALDDVL
     VFHAGTKQSA TDLVASGGRV LNVVGLGKTV SEAQARAYRG VDAIDWPEGF CRRDIGWQAV
     KREREG
//
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