ID A0A1B3PGL0_9BURK Unreviewed; 387 AA.
AC A0A1B3PGL0;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Mechanosensitive ion channel family protein {ECO:0000313|EMBL:AOG21912.1};
GN ORFNames=BSY15_1191 {ECO:0000313|EMBL:AOG21912.1};
OS Acidovorax sp. RAC01.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Acidovorax.
OX NCBI_TaxID=1842533 {ECO:0000313|EMBL:AOG21912.1, ECO:0000313|Proteomes:UP000094760};
RN [1] {ECO:0000313|Proteomes:UP000094760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RAC01 {ECO:0000313|Proteomes:UP000094760};
RA Florea S., Webb J.S., Jaromczyk J., Schardl C.L.;
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; CP016447; AOG21912.1; -; Genomic_DNA.
DR RefSeq; WP_069106415.1; NZ_CP016447.1.
DR AlphaFoldDB; A0A1B3PGL0; -.
DR KEGG; acra:BSY15_1191; -.
DR PATRIC; fig|1842533.3.peg.1231; -.
DR OrthoDB; 9775207at2; -.
DR Proteomes; UP000094760; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049142; MS_channel_1st.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30566:SF25; INNER MEMBRANE PROTEIN-RELATED; 1.
DR PANTHER; PTHR30566; YNAI-RELATED MECHANOSENSITIVE ION CHANNEL; 1.
DR Pfam; PF21088; MS_channel_1st; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000094760};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 147..186
FT /note="Mechanosensitive ion channel transmembrane helices
FT 2/3"
FT /evidence="ECO:0000259|Pfam:PF21088"
FT DOMAIN 188..253
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 260..345
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
FT REGION 357..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 387 AA; 41211 MW; 8622AA7C29DC4F68 CRC64;
MQQPLFITWI QETTFAGVPL WSLLVALTAA AVTYMAILTA LHLLTGRAKS WATNSGSAAA
TTMVDVLEGT SRLLMLLVAV LVGLGFLELP RRWESRVAQL WFVAVALQMG LWGMRAIGIG
VQRYVTRHSS SGMTQVSASA TLLSWGLRTL LWSVVALAVL SNLGVNITAF VASLGVGGIA
VALAVQSILA DLFASLSIAV DKPFEVGDFV VVGSVAGTVQ MIGLKTTRIR SLQGEEVVMS
NTDILKQTIS NYRPMQEQRI VFTFGVAYGT PVDKVEAIPG VVRQLVEAQA ALRFDRAHFK
GFGDSSLDFE VVYIVKDPGF NVYMDLQQTI NLGLMRELAA MGVEFAFPTR TIHIATVPTG
QPRTSPGATP GAADAAAGPL AALSAQA
//
