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Database: UniProt
Entry: A0A1B4WRK5_SIV
LinkDB: A0A1B4WRK5_SIV
Original site: A0A1B4WRK5_SIV 
ID   A0A1B4WRK5_SIV          Unreviewed;       231 AA.
AC   A0A1B4WRK5;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   12-AUG-2020, entry version 12.
DE   RecName: Full=Protein Nef {ECO:0000256|RuleBase:RU000344};
GN   Name=nef {ECO:0000313|EMBL:BAV25184.1};
OS   Simian immunodeficiency virus - agm.
OC   Viruses; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
OX   NCBI_TaxID=11726 {ECO:0000313|EMBL:BAV25184.1, ECO:0000313|Proteomes:UP000146425};
RN   [1] {ECO:0000313|Proteomes:UP000146425}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Carr M., Kawaguchi A., Sasaki M., Gonzalez G., Ito K., Nakamura I.,
RA   Thomas Y., Hangombe B., Mweene A., Wang D., Orba Y., Sawa H., Ishii A.;
RT   "Isolation of a Simian Immunodeficiency Virus from the Malbrouck
RT   (Chlorocebus cynosuros).";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the lentivirus primate group Nef protein family.
CC       {ECO:0000256|ARBA:ARBA00006933, ECO:0000256|RuleBase:RU000344}.
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DR   EMBL; LC114462; BAV25184.1; -; Genomic_RNA.
DR   SMR; A0A1B4WRK5; -.
DR   Proteomes; UP000146425; Genome.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0030683; P:mitigation of host immune response by virus; IEA:UniProtKB-KW.
DR   GO; GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.62.10; -; 1.
DR   InterPro; IPR027481; HIV-1_Nef_core_sf.
DR   InterPro; IPR001558; HIV_Nef.
DR   Pfam; PF00469; F-protein; 1.
DR   SUPFAM; SSF55671; SSF55671; 1.
PE   3: Inferred from homology;
KW   Host-virus interaction {ECO:0000256|ARBA:ARBA00022581};
KW   Lipoprotein {ECO:0000256|RuleBase:RU000344};
KW   Myristate {ECO:0000256|ARBA:ARBA00022707, ECO:0000256|RuleBase:RU000344};
KW   Reference proteome {ECO:0000313|Proteomes:UP000146425};
KW   Viral immunoevasion {ECO:0000256|ARBA:ARBA00023280,
KW   ECO:0000256|RuleBase:RU000344};
KW   Virulence {ECO:0000256|ARBA:ARBA00023026, ECO:0000256|RuleBase:RU000344}.
SQ   SEQUENCE   231 AA;  26529 MW;  AC7E0B6F7D6B54A8 CRC64;
     MGSGNSKPQH KKQLALWRAL HKTQPTRYGL LADPLIGQSS TLQEECGRSV RESLIKKRPT
     KGRMTPEGRR LQEGDTWEEW SDDEEEIGFP VKPRVPLRQM TYKLAVDFSH FLKEKGGLEG
     IYYSERRDKI LNLYALNEWG ILDDWNAWTP GPGIRYPRCF GFCFKLVPVE LHEEAQNCER
     HCLVHPAQMI EDPDGINHGE VLVWKFDPML AVEFKAGIHF SDMHATVGKG N
//
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