ID A0A1B6AH17_9ACTN Unreviewed; 344 AA.
AC A0A1B6AH17;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Putative branched-chain alpha-keto acid dehydrogenase E1 component beta subunit {ECO:0000313|EMBL:GAU66617.1};
GN Name=bkdB {ECO:0000313|EMBL:GAU66617.1};
GN ORFNames=SSP35_03_02650 {ECO:0000313|EMBL:GAU66617.1};
OS Streptomyces sp. NBRC 110611.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1621259 {ECO:0000313|EMBL:GAU66617.1, ECO:0000313|Proteomes:UP000094479};
RN [1] {ECO:0000313|EMBL:GAU66617.1, ECO:0000313|Proteomes:UP000094479}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 110611 {ECO:0000313|EMBL:GAU66617.1,
RC ECO:0000313|Proteomes:UP000094479};
RA Igarashi Y., Komaki H., Ichikawa N., Hosoyama A., Fujita N., Panbangred W.;
RT "Whole genome shotgun sequence of Streptomyces sp. NBRC 110611.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAU66617.1}.
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DR EMBL; BBUY01000003; GAU66617.1; -; Genomic_DNA.
DR RefSeq; WP_066928993.1; NZ_BBUY01000003.1.
DR AlphaFoldDB; A0A1B6AH17; -.
DR STRING; 1621259.GCA_001590865_01928; -.
DR OrthoDB; 3457658at2; -.
DR Proteomes; UP000094479; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000094479}.
FT DOMAIN 13..188
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 344 AA; 37187 MW; C819447481F44FB4 CRC64;
MTTTAPETAR RSATMAQALN RALRDAMAED PSVHVMGEDV GALGGVFRVT DGLVREFGED
RCTDTALAEA GILGTAVGMA MYGLRPVVEM QFDAFAYPAF EQLVSHVSRM RNRTRGALPM
PLTIRIPYGG GIGGVEHHSD SSEAYYLATP GLQVVTPATV EDAYGLLRAA IATDDPVVFL
EPKRLYWSKA DWSPDAPAPV APLGRAVVRR RGSSATLITY GPSLPACLEA AEAARAEGWD
LEVVDLRSLV PFDDETVCAS VRRTGRAVIV HEATGFGGPG GEIAARITER CFHHLEAPVL
RVTGFDIPYP PPMLERHHLP GVDRILDTVA RLQWESEWTE GRGE
//
