ID A0A1B6AM46_9ACTN Unreviewed; 463 AA.
AC A0A1B6AM46;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Cation/H+ exchanger domain-containing protein {ECO:0000259|Pfam:PF00999};
GN ORFNames=SSP35_08_02420 {ECO:0000313|EMBL:GAU68748.1};
OS Streptomyces sp. NBRC 110611.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1621259 {ECO:0000313|EMBL:GAU68748.1, ECO:0000313|Proteomes:UP000094479};
RN [1] {ECO:0000313|EMBL:GAU68748.1, ECO:0000313|Proteomes:UP000094479}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 110611 {ECO:0000313|EMBL:GAU68748.1,
RC ECO:0000313|Proteomes:UP000094479};
RA Igarashi Y., Komaki H., Ichikawa N., Hosoyama A., Fujita N., Panbangred W.;
RT "Whole genome shotgun sequence of Streptomyces sp. NBRC 110611.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAU68748.1}.
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DR EMBL; BBUY01000008; GAU68748.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B6AM46; -.
DR STRING; 1621259.GCA_001590865_04067; -.
DR OrthoDB; 9793589at2; -.
DR Proteomes; UP000094479; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR32468; CATION/H + ANTIPORTER; 1.
DR PANTHER; PTHR32468:SF0; K(+)_H(+) ANTIPORTER 1; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000094479};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 44..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..430
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 58..431
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
FT REGION 444..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 463 AA; 47540 MW; FDCE2BC3933D8C27 CRC64;
MGFFPVGYFP LSFCPRGLLP LSFSPCVLCV LCVLSECSPM TGNIVADFFL ALSLTLGAAR
IFGALARRVA QPAVVGEICA GLLVSPMVLT RAGADAVLSA EVTPLLGALA NVGLATFMFL
IGYEIDGAFL RHRRKATLGV ATGAVAVPLA AGVAVAIPLA QAYAPGNRTA FVLFVGVAMS
VTAFPVLARI LADRGLSRHP VGSLTLAAAA VGDLVAWICL AAVAAYAGAA GQWQLALLPV
YLVVLVAGVR PLLATLLERA RRRGVAAERL VPALVVGLAL SCAVTEWLGV HFIFGAFAFG
AVMPRNALDG VRSTIMRHME QVGQVLLPLY FVLAGTKVDL SAFGVTALLT LVAVIGVAVL
SKAGGAYGGA RLAGLPHAAA LPAAVLMNTR GLTEIVIVAV ALDMGLINQD FYSMMVVMAV
VTTAMTGPLL KLFGVLPQDP SVHQPDLAAS SPGALPKKAA KTG
//
