ID   A0A1B6AMI9_9ACTN        Unreviewed;       412 AA.
AC   A0A1B6AMI9;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE            EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN   Name=holB {ECO:0000313|EMBL:GAU68770.1};
GN   ORFNames=SSP35_09_00130 {ECO:0000313|EMBL:GAU68770.1};
OS   Streptomyces sp. NBRC 110611.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1621259 {ECO:0000313|EMBL:GAU68770.1, ECO:0000313|Proteomes:UP000094479};
RN   [1] {ECO:0000313|EMBL:GAU68770.1, ECO:0000313|Proteomes:UP000094479}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 110611 {ECO:0000313|EMBL:GAU68770.1,
RC   ECO:0000313|Proteomes:UP000094479};
RA   Igarashi Y., Komaki H., Ichikawa N., Hosoyama A., Fujita N., Panbangred W.;
RT   "Whole genome shotgun sequence of Streptomyces sp. NBRC 110611.";
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAU68770.1}.
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DR   EMBL; BBUY01000009; GAU68770.1; -; Genomic_DNA.
DR   RefSeq; WP_066933487.1; NZ_BBUY01000009.1.
DR   AlphaFoldDB; A0A1B6AMI9; -.
DR   STRING; 1621259.GCA_001590865_04087; -.
DR   OrthoDB; 9809531at2; -.
DR   Proteomes; UP000094479; Unassembled WGS sequence.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR004622; DNA_pol_HolB.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   NCBIfam; TIGR00678; holB; 1.
DR   PANTHER; PTHR11669:SF70; POSSIBLE DNA POLYMERASE; 1.
DR   PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR   Pfam; PF13177; DNA_pol3_delta2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   Reference proteome {ECO:0000313|Proteomes:UP000094479};
KW   Transferase {ECO:0000256|ARBA:ARBA00022932}.
FT   COILED          262..289
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   412 AA;  43521 MW;  8D1ED1872EEFC8C6 CRC64;
     MAVWDDLVGQ DRVTAQLAAA ARDADAIVTA EHAESAGSAG AAQGPSADRV SASQMTHAWL
     FTGPPGSGRS SVARAFAAAL QCSHHGAGVP GCGFCDGCHT TMVGTHADVE IVRTDLLSIG
     VKETRDLVRR SSLSPAGGRW QVIVLEDADR LTEGAGNVLL KAVEEPAPRT VWLLCAPSIE
     DVLPTIRSRC RHLSLRTPPV DAVADLLVRR DGIEPEAAAR AARASQGHIG RARRLATDER
     ARARRAAVLK LPLRIDDIGG CLKAAQELID AAGEDAKQVA EEVDAKETEE LRAALGAAAG
     TGGRLPRGTA GVMKELQDKQ KRRATRTQRD SLDLALVDLT GFYRDVLALQ MGAPVPLAND
     EVRDSVQRVA AGSTPERTLR RIEAVIACRE ALDRNVAPLL AVEAMTASLR AA
//