ID A0A1B6B746_9FIRM Unreviewed; 1147 AA.
AC A0A1B6B746;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=F3D3_0141 {ECO:0000313|EMBL:GAU75550.1};
OS Fusibacter sp. 3D3.
OC Bacteria; Bacillota; Clostridia; Eubacteriales;
OC Eubacteriales Family XII. Incertae Sedis; Fusibacter.
OX NCBI_TaxID=1048380 {ECO:0000313|EMBL:GAU75550.1, ECO:0000313|Proteomes:UP000095197};
RN [1] {ECO:0000313|EMBL:GAU75550.1, ECO:0000313|Proteomes:UP000095197}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3D3 {ECO:0000313|EMBL:GAU75550.1,
RC ECO:0000313|Proteomes:UP000095197};
RA Serrano A.E., Escudero L.V., Encalada O., Tebes C.J., Fernandez S.,
RA Demergasso C.S.;
RT "Draft genome sequence of Fusibacter ascotence 3D3 isolated from the high
RT arsenic level Ascotan salt flat in northern Chile.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC -!- SIMILARITY: Belongs to the tRNA methyltransferase O family.
CC {ECO:0000256|ARBA:ARBA00033753}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAU75550.1}.
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DR EMBL; BDHH01000001; GAU75550.1; -; Genomic_DNA.
DR RefSeq; WP_069870220.1; NZ_BDHH01000001.1.
DR AlphaFoldDB; A0A1B6B746; -.
DR STRING; 1048380.F3D3_0141; -.
DR Proteomes; UP000095197; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 2.40.30.70; YaeB-like; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR023370; TrmO-like_N.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR036413; YaeB-like_sf.
DR InterPro; IPR036414; YaeB_N_sf.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF01980; TrmO; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF118196; YaeB-like; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS51668; TSAA_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000095197};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 128..255
FT /note="TsaA-like"
FT /evidence="ECO:0000259|PROSITE:PS51668"
SQ SEQUENCE 1147 AA; 128207 MW; F424726DAAFB43E5 CRC64;
MKKIELLPIG VVRESVLSPL KAKRQLKIEI EEGYKMALNH LDLFSNCLIF WMTDDGIHME
GAEVLACAPK RGSLNVALNT AWMPEGLLID IKPYFPCEDQ IREPNSGKND SNLPHIIQNP
SAYIRFTHEP IGKFVRHDNV ESLKICSIGA VDFKTIEKKV RRGDHLSVIW WFDRFDKSEY
RKLTMCNPPY PNSPRCGIFA TRSPVRPNPI ASTVVKVVAV DVEGQKIDVL GFDGFDNSHI
LQISPYVACD FLENRVPKWV DHWTPYKVFQ TYEAVQISLE SAQENLDTLS TLVASDLYVE
ALEPKVLLNE MKASDYPLNQ IVLEGVKTHN LKGISLSIPK EKITTITGVS GSGKSSLAFD
TLFAESQKQY MDLLMSNAPS QLAKIHSHVS KIHGLQPAIA IEQKSIGRNP RSTVGSVSKA
SDFLKQLYVT IGERVCPQCQ RVIPEDLICE TCGSVFFSMT PSDFSANNPE YMCPNCKGLG
YDFQIDVERI ITHPERSILE GASEWWGNLR KHREKPNANW MRGEALALAA DMNEDLEVPF
KDLSEAYKAQ LFYGSNGRVV SLTYENSNGR KGTISRPVEG VFNTIWRLLK DSTLDNTMRH
MERFLKKETC KRCHGEKLIE ASRLVNIEHI RYPQALNLSV ADLKRWCHAV YFNLSEEKKI
KTKSIFIELL QKLKRLEEVG LGYLGLDRSV VTLSGGELQR LKIASQFGSD LSNILYIMDE
PSKGLHPKDY KFLIESIESL KASGNTVVIV EHKKAFIDRA DYIVEIGPGA GHYGGELIRA
ESQNRERVSD EGAIEEAVQG SVEGSVEGSV EGLVESENEF KFELTVATPH EQKAKIDWIE
MNGAKTYNLK SVDFQIPRSK MTAVIGVSGS GKSSLVSKTL YPALCKKIGI MDVEQGQFNA
LKGVDHIESV DLMNQQAIGR NSRSTPATYT GVLDLMRVFY AKLDHAKAMQ LTKEHFSFNS
SKGQCDKCKG IGEIITPMHF MPDLYSVCES CHGKRYKPEI LEVFYKGHSI ADVLDMEIGD
AKIAFEDVPQ IFSILKMLDR VGLGYLKLGQ SASTLSGGEA QRIRLAKTLV EGKLKGAVYI
LDEPTTGLQD TDVKRLLPIF KEMTDHGATI IAIEHNPLLI SASDYIVELG PEGGHNGGYI
MREGWMA
//
