ID A0A1B6BCG8_9FIRM Unreviewed; 949 AA.
AC A0A1B6BCG8;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Cell division protein peptidoglycan synthetase FtsI {ECO:0000313|EMBL:GAU77420.1};
DE EC=2.4.1.129 {ECO:0000313|EMBL:GAU77420.1};
GN ORFNames=F3D3_2049 {ECO:0000313|EMBL:GAU77420.1};
OS Fusibacter sp. 3D3.
OC Bacteria; Bacillota; Clostridia; Eubacteriales;
OC Eubacteriales Family XII. Incertae Sedis; Fusibacter.
OX NCBI_TaxID=1048380 {ECO:0000313|EMBL:GAU77420.1, ECO:0000313|Proteomes:UP000095197};
RN [1] {ECO:0000313|EMBL:GAU77420.1, ECO:0000313|Proteomes:UP000095197}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3D3 {ECO:0000313|EMBL:GAU77420.1,
RC ECO:0000313|Proteomes:UP000095197};
RA Serrano A.E., Escudero L.V., Encalada O., Tebes C.J., Fernandez S.,
RA Demergasso C.S.;
RT "Draft genome sequence of Fusibacter ascotence 3D3 isolated from the high
RT arsenic level Ascotan salt flat in northern Chile.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAU77420.1}.
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DR EMBL; BDHH01000007; GAU77420.1; -; Genomic_DNA.
DR RefSeq; WP_069873504.1; NZ_BDHH01000007.1.
DR AlphaFoldDB; A0A1B6BCG8; -.
DR STRING; 1048380.F3D3_2049; -.
DR OrthoDB; 9757901at2; -.
DR Proteomes; UP000095197; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 2.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 2.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 2.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:GAU77420.1};
KW Cell division {ECO:0000313|EMBL:GAU77420.1};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Glycosyltransferase {ECO:0000313|EMBL:GAU77420.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000095197};
KW Transferase {ECO:0000313|EMBL:GAU77420.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 52..352
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 420..601
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT DOMAIN 685..789
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT COILED 826..853
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 949 AA; 107831 MW; BB79F3B27448A87A CRC64;
MLKLIFNRKN QIIIFFVIVF SLLGYRLYML TIVDGEMYYS KSINNRIKQI ETYAKRGDIY
DRNGEVLATS NVGFVLKLNS GVIPAEDFTT YAIGLYDFLE EAEESHIEFP IIFKNGEYRY
VYDDNIKKWK EVNGYDQSMT AADIFREVRS RNYLDTSLSD YEAFKILYNQ GKYVPISTSK
MKFLDEIYKS TFLKMYGVDE GATAKEAFER IRKRTDFKIS AELPDEDAYK VLVFRHAIKE
KGYYKYEPIV IAPSIKHETT VKIQEKGFEF PGTSVSYESI RTYPNGSTAA HILGYMGKIS
TESETSKFVT QNKYNPNQVI GKVGIEGNYE LDLHGENGYK YIEVDVYGKY VQDVDEKAYG
LEAKNATSGD EIYLTIDLSL QKTLEASLEK ALKGIQKGGK FESPWGDYDY GDAFPQAETG
AAVAVNVNTG EILAMASYPS YDINLFSTGI SQEDWNSLNP VNTRNPLAAR PLFNTATMMA
TQPGSIYKMI TGFAAMEQGL DPYLKLYDNG YVEVGNQRYA CWMWNDYRAR HGLVDMLRAI
EVSCNYYFFD VATGKDFYKN KPLNYTITPQ IIVDESKKFG LDEPTGIEIG ESSFGIPDPD
KKKRTIKILL SRHLKNISKN YFSDDISKDP EKLQAVIDEI VSWADENPSR GDIIQKLIDM
GANSDYYVTE KLADIIKYDY FNLMKWYEGD TLNLSIGQGD HTYTPVQMAR YIAALANGGY
LKELSVVKKV GDESIVKNRE EQVSFDTHGY IDILQEGMLR VSKGSEGTAR KIFGTFPIDV
AAKTGTAEKE GLIPPLDEIQ YLSEYLSAFA PRLELADVEN RTIEIIKERS EELSKLEKSK
DEETDEAIRL EKEEKLNLLI ARDYLNKGDA MRAAIKELSG DMLTDEEINQ YRLPYDNYSW
FVSFAPFDDP ELAVVVVIPQ GGHGAYGAPV ARDVFADYFK LSVPEEPEK
//
