ID A0A1B6QD81_SORBI Unreviewed; 1135 AA.
AC A0A1B6QD81;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=SORBI_3002G239700 {ECO:0000313|EMBL:KXG35861.1};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:KXG35861.1, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:KXG35861.1, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR EMBL; CM000761; KXG35861.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B6QD81; -.
DR EnsemblPlants; KXG35861; KXG35861; SORBI_3002G239700.
DR Gramene; KXG35861; KXG35861; SORBI_3002G239700.
DR eggNOG; ENOG502QSU9; Eukaryota.
DR InParanoid; A0A1B6QD81; -.
DR OMA; LLRWKDT; -.
DR Proteomes; UP000000768; Chromosome 2.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 5.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR27008; OS04G0122200 PROTEIN; 1.
DR PANTHER; PTHR27008:SF486; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 7.
DR Pfam; PF13855; LRR_8; 3.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00369; LRR_TYP; 9.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 2.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000000768};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 802..1090
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1090..1135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..42
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1116..1135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 831
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1135 AA; 119924 MW; F0B969B976F7ACDE CRC64;
MLARGATSQS QPSTALPPPL SSRHPPASAS PPRRAPPMPP RSRAAAPRLA FLVPLACALL
LVSLSPCHCV NEQGQALLRW KDTLRPASGA LASWRAADAN PCRWTGVSCN ARGDVVGLSI
TSVDLQGPLP ANLQPLAASL KTLELSGTNL TGAIPKEMGG YGELTTLDLS KNQLTGAIPD
ELCRLAKLES LALNSNSLRG AIPDDIGNLT SLAYLTLYDN ELSGPIPPSI GNLKKLQVLR
AGGNQGMKGP LPPEIGGCSN LTMLGLAETG VSGSLPETIG QLKKIQTIAI YTTLLSGRIP
ESIGNCTELT SLYLYQNSLS GPIPAQLGQL KKLQTLLLWQ NQLVGAIPPE LGQCKELTLI
DLSLNSLTGS IPASLGRLPN LQQLQLSTNQ LTGTIPPELS NCTSLTDIEV DNNLLSGEIS
IDFPRLSNLT LFYAWKNRLT GGVPVSLAEA PSLQAVDLSY NNLTGPIPKA LFGLQNLTKL
LLLNNELSGP IPPEIGNCTN LYRLRLNGNR LSGTIPAEIG NLKNLNFLDM SENHLVGPVP
AAISGCASLE FLDLHSNALS GALPDTLPRS LQLIDVSDNQ LAGPLSSSIG SMPELTKLYM
GNNRLTGGIP PELGSCEKLQ LLDLGGNAFS GDIPSELGLL PSLEISLNLS SNRLSGEIPS
QFAGLDKLGS LDLSHNELSG SLEPLAALQN LVTLNISYNA FSGELPNTPF FQKLPLSDLA
GNRHLVVGDG SDESSRRGAI SSLKIAMSVL ATVSALLLVS ATYMLARTHR RGGGRIIHGE
GSWEVTLYQK LDITMDDVLR GLTSANMIGT GSSGAVYKVD TPNGYTLAVK KMWSSDEATS
AAFRSEIAAL GSIRHRNIVR LLGWAANGGT RLLFYGYLPN GSLSGLLHGG HAGKGSPADE
WGARYEIALG VAHAVAYLHH DCVPAILHGD VKSMNVLLGP AYEPYLADFG LARVLAAATS
KLDTGKQPRI AGSYGYMAPE YASMQRISEK SDVYSFGVVL LEILTGRHPL DPTLSGGAHL
VQWVREHVQA KRDAAELLDA RLRGRASEAD VHEMRQVLSV AALCVSRRAD DRPAMKDVVA
LLKEIRRPAA VDDAKQPSPT ATGAAATPAP VSPVVSAHSR GQSSSCSFAV SEYSA
//
