ID A0A1B6YSV0_9RHOB Unreviewed; 403 AA.
AC A0A1B6YSV0;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:OAN72599.1};
GN ORFNames=A8B83_09520 {ECO:0000313|EMBL:OAN72599.1};
OS Rhodobacteraceae bacterium EhC02.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae.
OX NCBI_TaxID=1849170 {ECO:0000313|EMBL:OAN72599.1, ECO:0000313|Proteomes:UP000078223};
RN [1] {ECO:0000313|EMBL:OAN72599.1, ECO:0000313|Proteomes:UP000078223}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EhC02 {ECO:0000313|EMBL:OAN72599.1,
RC ECO:0000313|Proteomes:UP000078223};
RA Lavstsen T., Jespersen J.S.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAN72599.1}.
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DR EMBL; LXYH01000005; OAN72599.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B6YSV0; -.
DR STRING; 1849170.A8B83_09520; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000078223; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43365; BLR7806 PROTEIN; 1.
DR PANTHER; PTHR43365:SF1; STEROID 3-KETOACYL-COA THIOLASE FADA6; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000078223};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:OAN72599.1}.
FT DOMAIN 4..233
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 281..402
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 91
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 359
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 389
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 403 AA; 42530 MW; EDFC36F8D3C5528D CRC64;
MTDVYIYDAI RTPRGKGRAD GSLHEVTSAR ISAQVLNALK ERNGFEGHAV EDVIWGNVTQ
VMEQGACLAR TAVLASDLDE SIPGLAINRF CASGMEAVNL AANQVRGGAG MGYIAGGVEM
MSRVPMGSDG AAIAVDPSIA MDSYFVPQGI SADIIATEYG FSRDEADALA VESQRRAKAA
WDDKRFAKSI VPVVDQNGLT ILGHDEFMRP QTDMQSLGAL KPSFKDMGEV MPGFDKVALM
KYPHLELINH IHHAGNSSGI VDGAAGVLIG NKEFGEKWGI KPRARIKATC KIGTDPTIML
TGPVPATQKI LADSGMSISD IDLFEVNEAF ASVVLRFMQA FDVDSSVVNV NGGSIAMGHP
LGATGAMIIG TLLDELERTG KGTGLATLCI ASGMGAATII ERV
//
