ID A0A1B7JVI0_9GAMM Unreviewed; 352 AA.
AC A0A1B7JVI0;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=ECA polysaccharide chain length modulation protein {ECO:0000256|HAMAP-Rule:MF_02025};
GN Name=wzzE {ECO:0000256|HAMAP-Rule:MF_02025};
GN ORFNames=M998_1909 {ECO:0000313|EMBL:OAT51910.1};
OS Providencia heimbachae ATCC 35613.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Providencia.
OX NCBI_TaxID=1354272 {ECO:0000313|EMBL:OAT51910.1, ECO:0000313|Proteomes:UP000078224};
RN [1] {ECO:0000313|EMBL:OAT51910.1, ECO:0000313|Proteomes:UP000078224}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35613 {ECO:0000313|EMBL:OAT51910.1,
RC ECO:0000313|Proteomes:UP000078224};
RA Plunkett G.III., Neeno-Eckwall E.C., Glasner J.D., Perna N.T.;
RT "ATOL: Assembling a taxonomically balanced genome-scale reconstruction of
RT the evolutionary history of the Enterobacteriaceae.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Modulates the polysaccharide chain length of enterobacterial
CC common antigen (ECA). {ECO:0000256|HAMAP-Rule:MF_02025}.
CC -!- PATHWAY: Bacterial outer membrane biogenesis; enterobacterial common
CC antigen biosynthesis. {ECO:0000256|HAMAP-Rule:MF_02025}.
CC -!- SUBUNIT: Probably part of a complex composed of WzxE, WzyE and WzzE.
CC {ECO:0000256|HAMAP-Rule:MF_02025}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC Rule:MF_02025}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_02025}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass
CC membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the WzzB/Cld/Rol family. {ECO:0000256|HAMAP-
CC Rule:MF_02025}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAT51910.1}.
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DR EMBL; LXEW01000027; OAT51910.1; -; Genomic_DNA.
DR RefSeq; WP_068908611.1; NZ_LXEW01000027.1.
DR AlphaFoldDB; A0A1B7JVI0; -.
DR GeneID; 79029723; -.
DR PATRIC; fig|1354272.4.peg.1941; -.
DR OrthoDB; 9775724at2; -.
DR UniPathway; UPA00566; -.
DR Proteomes; UP000078224; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009246; P:enterobacterial common antigen biosynthetic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.1890.10; FepE-like; 1.
DR HAMAP; MF_02025; WzzE; 1.
DR InterPro; IPR003856; LPS_length_determ_N_term.
DR InterPro; IPR032895; WzzE.
DR PANTHER; PTHR32309:SF16; ECA POLYSACCHARIDE CHAIN LENGTH MODULATION PROTEIN; 1.
DR PANTHER; PTHR32309; TYROSINE-PROTEIN KINASE; 1.
DR Pfam; PF02706; Wzz; 1.
DR SUPFAM; SSF160355; Bacterial polysaccharide co-polymerase-like; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_02025};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_02025};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_02025};
KW Reference proteome {ECO:0000313|Proteomes:UP000078224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_02025};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_02025}.
FT TRANSMEM 33..53
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_02025"
FT TRANSMEM 327..346
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_02025"
FT DOMAIN 18..86
FT /note="Polysaccharide chain length determinant N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02706"
SQ SEQUENCE 352 AA; 39779 MW; 11D1483A1158D551 CRC64;
MNNSETQPNQ YQAPVEPELD IRGLCRSLWQ GKIWIAAFAV IFAAIALGAS YFMQPKWSST
AITDLPTVNN LGSYYSQQQF LRNLDSRINN IGQEGQLPTI AKEAYEEFTK QLGAYDTRRQ
FWLSTDYYKQ RLENDPKADA ALLDELINNI EFTPADELKN LTDSIKLVAE TATDSNQLLR
EYIQFANQRA TTNLNDEIKG TWATKMQSMK ALVKREDMVA QAAYERRLNT LEQALIVAEK
QGISRNQSSM PVDEVPDSKM FMLGAPLLQA QIETLKATGP DHDSNYDQNI AMLSTLSVGP
TLQDNFQAYR YLRTPEDPVK RDSPRRAFMM VLWGAIGMLV GAGVVLSRRR PS
//
