ID A0A1B7LII1_9FIRM Unreviewed; 480 AA.
AC A0A1B7LII1;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=4-hydroxybutyryl-CoA dehydratase {ECO:0000313|EMBL:OAT86380.1};
GN ORFNames=A6M21_16625 {ECO:0000313|EMBL:OAT86380.1};
OS Desulfotomaculum copahuensis.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfotomaculaceae;
OC Desulfotomaculum.
OX NCBI_TaxID=1838280 {ECO:0000313|EMBL:OAT86380.1, ECO:0000313|Proteomes:UP000078532};
RN [1] {ECO:0000313|EMBL:OAT86380.1, ECO:0000313|Proteomes:UP000078532}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMa1 {ECO:0000313|EMBL:OAT86380.1,
RC ECO:0000313|Proteomes:UP000078532};
RA Evans L.H., Alamgir A., Owens N., Weber N.D., Virtaneva K., Barbian K.,
RA Babar A., Rosenke K.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAT86380.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LYVF01000017; OAT86380.1; -; Genomic_DNA.
DR RefSeq; WP_066666307.1; NZ_LYVF01000017.1.
DR AlphaFoldDB; A0A1B7LII1; -.
DR STRING; 1838280.A6M21_16625; -.
DR OrthoDB; 9785230at2; -.
DR Proteomes; UP000078532; Unassembled WGS sequence.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 1.10.3140.10; 4-hydroxybutyryl-coa dehydratase, domain 1; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR InterPro; IPR004925; HpaB/PvcC/4-BUDH.
DR InterPro; IPR024719; HpaB/PvcC/4-BUDH_C.
DR InterPro; IPR024674; HpaB/PvcC/4-BUDH_N.
DR PANTHER; PTHR36117; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR36117:SF3; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR Pfam; PF03241; HpaB; 1.
DR Pfam; PF11794; HpaB_N; 1.
DR PIRSF; PIRSF000331; HpaA_HpaB; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|PIRSR:PIRSR000331-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000078532}.
FT DOMAIN 3..273
FT /note="HpaB/PvcC/4-BUDH N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11794"
FT DOMAIN 280..475
FT /note="HpaB/PvcC/4-BUDH C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03241"
FT BINDING 189
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
SQ SEQUENCE 480 AA; 53543 MW; BA15ED74F2B06C8B CRC64;
MLTGEEYIES LRHLKTEIYA FGERIANFVD HPLFRPHINA AAVTYDMAHE SEFEDLVTVH
SHLTGKKINR FTHIHQSSED LVKKVKMLRM IAQRTGTCFQ RCVGFDGLNA LYSVTYEMDQ
TLGTSYHQHF VDFLKYVQEK DLMSAGSMTD PKGDRSLRPS QQADPDMYVH VVKKMAEGIV
IRGAKAHQTG IINSHYMIIM PTIALGEADQ DYAVSCAVPV DAPGVFHIFG RQTNDERRLD
GEIDIGNARY GIVGGEALTV LEDVFIPWER VFMCGEYQFA GMLVERFASF HRQNYGGCKC
GVSDIIIGAT MVLAEYNGVA KASHIKDKIT EMLHLSETLY CCSIACSAEG RKTLSGAYFV
NPLLANVVKQ NVTRHIYEIC RLAHDVAGGF IATLPSEKDF QNAKTGPYLE KYFSGVVGVP
TENRVRMARL VENMTGGTAL AESMHGAGSP QTQRVMIIRQ SNIEHKKRMA KKLAGVPEQK
//
