ID A0A1B7M2J8_9MICC Unreviewed; 565 AA.
AC A0A1B7M2J8;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=DNA (cytosine-5-)-methyltransferase {ECO:0000256|ARBA:ARBA00011975};
DE EC=2.1.1.37 {ECO:0000256|ARBA:ARBA00011975};
GN ORFNames=A6F49_04820 {ECO:0000313|EMBL:OAV62832.1};
OS Enteractinococcus helveticum.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae.
OX NCBI_TaxID=1837282 {ECO:0000313|EMBL:OAV62832.1, ECO:0000313|Proteomes:UP000078292};
RN [1] {ECO:0000313|EMBL:OAV62832.1, ECO:0000313|Proteomes:UP000078292}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UASWS1574 {ECO:0000313|EMBL:OAV62832.1,
RC ECO:0000313|Proteomes:UP000078292};
RA Crovadore J., Chablais R., Lefort F.;
RT "First whole genome shotgun sequence of the bacterium Enteractinococcus sp.
RT strain UASWS1574.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. C5-methyltransferase family. {ECO:0000256|PROSITE-
CC ProRule:PRU01016}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAV62832.1}.
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DR EMBL; LXEY01000008; OAV62832.1; -; Genomic_DNA.
DR RefSeq; WP_052499959.1; NZ_LXEY01000008.1.
DR AlphaFoldDB; A0A1B7M2J8; -.
DR STRING; 1837282.A6F49_04820; -.
DR REBASE; 164996; M.Ehe1574ORF4820P.
DR OrthoDB; 9813719at2; -.
DR Proteomes; UP000078292; Unassembled WGS sequence.
DR GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR Gene3D; 3.90.120.10; DNA Methylase, subunit A, domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR10629; CYTOSINE-SPECIFIC METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10629:SF52; DNA (CYTOSINE-5)-METHYLTRANSFERASE 1; 1.
DR Pfam; PF00145; DNA_methylase; 3.
DR PRINTS; PR00105; C5METTRFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51679; SAM_MT_C5; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01016}; Restriction system {ECO:0000256|ARBA:ARBA00022747};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01016};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01016}.
FT REGION 329..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..360
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 75
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01016"
SQ SEQUENCE 565 AA; 61465 MW; 972C9E3A4F231AB0 CRC64;
MHNSQQPSPL SAIDLFAGPG GWDVACQHLG IDVIGYEWDD AAVATREAAG HQSVHGDIRQ
YDPVAADLLI ASPSCQSFSV AGSGAGRRAL DQVLTDIEVI ASGRDIDLYG YDDERTAMVL
IPLIWALTMH QAGTPYRHIA FEQVPPVKPV WEAMLTVLET LGYRGQVGVL QAEAYGVPQT
RKRAILVASL DHDAKLPQQT HSKYHPRNPQ RLDDHVLPWV SMAEALGWGM TQRPTMTVTA
GGGATGGAEP FGNAARQGMK KARAEGKWED DICGAEVAVH PYFLQGNQKP TGQHYQRRNA
DTPAMAVTTQ SYLYKVGDAS TEQDSGDVYL ESNYSHNGDS SQRGKRSVTS PASTITSKSR
SQKFVRDDDG TDPLASGLVY DTNNTTRWGQ PDEVRYQRPI EYPAPTTTAS LSRHTIGPKG
FTTDQRRKAL EDHDRGAKIV PARNPVLRPS PYAGMLFNGS GRPLDQNRPA PVMTASAGGN
HSHIVDLTGG KFIESYHRDV AAGKQPPLAD APLRRLTAQE AAVLQTFPVD YPFQGTKTKV
FEQIGNAVPP LLAWHILSAL TDPQR
//
