ID A0A1B7N8Y3_9AGAM Unreviewed; 646 AA.
AC A0A1B7N8Y3;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Kinetochore protein NDC80 {ECO:0000256|RuleBase:RU368072};
GN ORFNames=K503DRAFT_863957 {ECO:0000313|EMBL:OAX41313.1};
OS Rhizopogon vinicolor AM-OR11-026.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Boletales; Suillineae; Rhizopogonaceae; Rhizopogon.
OX NCBI_TaxID=1314800 {ECO:0000313|EMBL:OAX41313.1, ECO:0000313|Proteomes:UP000092154};
RN [1] {ECO:0000313|EMBL:OAX41313.1, ECO:0000313|Proteomes:UP000092154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AM-OR11-026 {ECO:0000313|EMBL:OAX41313.1,
RC ECO:0000313|Proteomes:UP000092154};
RG DOE Joint Genome Institute;
RA Mujic A.B., Kuo A., Tritt A., Lipzen A., Chen C., Johnson J., Sharma A.,
RA Barry K., Grigoriev I.V., Spatafora J.W.;
RT "Comparative genomics of the ectomycorrhizal sister species Rhizopogon
RT vinicolor and Rhizopogon vesiculosus (Basidiomycota: Boletales) reveals a
RT divergence of the mating type B locus.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acts as a component of the essential kinetochore-associated
CC NDC80 complex, which is required for chromosome segregation and spindle
CC checkpoint activity. {ECO:0000256|RuleBase:RU368072}.
CC -!- SUBUNIT: Component of the NDC80 complex.
CC {ECO:0000256|RuleBase:RU368072}.
CC -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore
CC {ECO:0000256|RuleBase:RU368072}. Nucleus
CC {ECO:0000256|RuleBase:RU368072}.
CC -!- SIMILARITY: Belongs to the NDC80/HEC1 family.
CC {ECO:0000256|ARBA:ARBA00007050, ECO:0000256|RuleBase:RU368072}.
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DR EMBL; KV448184; OAX41313.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B7N8Y3; -.
DR STRING; 1314800.A0A1B7N8Y3; -.
DR InParanoid; A0A1B7N8Y3; -.
DR OrthoDB; 5490442at2759; -.
DR Proteomes; UP000092154; Unassembled WGS sequence.
DR GO; GO:0031262; C:Ndc80 complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051315; P:attachment of mitotic spindle microtubules to kinetochore; IEA:UniProtKB-UniRule.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR Gene3D; 6.10.250.1950; -; 1.
DR Gene3D; 1.10.418.30; Ncd80 complex, Ncd80 subunit; 1.
DR InterPro; IPR040967; DUF5595.
DR InterPro; IPR005550; Kinetochore_Ndc80.
DR InterPro; IPR038273; Ndc80_sf.
DR PANTHER; PTHR10643; KINETOCHORE PROTEIN NDC80; 1.
DR PANTHER; PTHR10643:SF2; KINETOCHORE PROTEIN NDC80 HOMOLOG; 1.
DR Pfam; PF18077; DUF5595; 1.
DR Pfam; PF03801; Ndc80_HEC; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|RuleBase:RU368072};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|RuleBase:RU368072};
KW Centromere {ECO:0000256|ARBA:ARBA00023328, ECO:0000256|RuleBase:RU368072};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454, ECO:0000256|RuleBase:RU368072};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Kinetochore {ECO:0000256|ARBA:ARBA00022838, ECO:0000256|RuleBase:RU368072};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776, ECO:0000256|RuleBase:RU368072};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU368072};
KW Reference proteome {ECO:0000313|Proteomes:UP000092154}.
FT DOMAIN 249..316
FT /note="DUF5595"
FT /evidence="ECO:0000259|Pfam:PF18077"
FT REGION 1..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 300..393
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 507..612
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 646 AA; 72812 MW; B57E7F70FC9BCB9F CRC64;
MSEARRRSTM QPATDLYGNA RSGLPMPSTA KKAAPSAMRM SLAGPAARTP YLPPPGVGSS
SNSAYRSQNA NPLLQSTSKP NYGRTPLTNS SRRGSIWTGG ASLAPPSGSQ TFKDPRPLRE
RSYQSKMKQD IYSWLQATEF DISMQTLSSI TGKDYRAMFQ HLVTIVDPAY PFDARLRFED
EFQPALKALR YPFAAQIDNK WLAAPGSMHS WPALLAVLHW LVEMGKARLN YLESEDDPTL
QIVDRIPEEF SDPIYHQALA FEYFSEAYVA FFHGADVFEE QDKALEARYA KKNERVAGDL
EEKKTLLAKT KKELDELQSS KAPLEKLQKI RACILDDRAK FDDVLHRLET RKKQLTESVA
REKVELATRL QNLEQLRAEH DKLTEVVKVQ NLTPEEVIRM STDHETLSRN LEDLKYKISE
AHKTVMSLEV VTTNRAAAAE EALDLYGNLL YGLGLSPPLP PPFENIDLRL ELNTATANPQ
QLLLGSDIRK VIKPTLNSVA EMKRSDRADI ESERIKVDNE LDQLSLECEN VDEEVREIEK
KVMSLNEQAD DLRDAAQQES MVSNAEAARL ERELAHARTA ALSSGMGVKS RLQALQFDYR
EQIAKVARLK DETIRAIAKN SNEIGLFKEE VSAQLRRLRD FVEEGT
//
