ID A0A1B7NVT1_9EURO Unreviewed; 673 AA.
AC A0A1B7NVT1;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=CBS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ACJ72_04784 {ECO:0000313|EMBL:OAX80874.1};
OS Emergomyces africanus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emergomyces.
OX NCBI_TaxID=1955775 {ECO:0000313|EMBL:OAX80874.1, ECO:0000313|Proteomes:UP000091918};
RN [1] {ECO:0000313|EMBL:OAX80874.1, ECO:0000313|Proteomes:UP000091918}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 136260 {ECO:0000313|EMBL:OAX80874.1,
RC ECO:0000313|Proteomes:UP000091918};
RA Cuomo C.A., Schwartz I.S., Kenyon C., de Hoog G.S., Govender N.P.,
RA Botha A., Moreno L., de Vries M., Munoz J.F., Stielow J.B.;
RT "Emmonsia species relationships and genome sequence.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAX80874.1}.
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DR EMBL; LGUA01000598; OAX80874.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B7NVT1; -.
DR STRING; 1658172.A0A1B7NVT1; -.
DR OrthoDB; 1328303at2759; -.
DR Proteomes; UP000091918; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd17781; CBS_pair_MUG70_1; 1.
DR CDD; cd17782; CBS_pair_MUG70_2; 1.
DR CDD; cd06409; PB1_MUG70; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR000270; PB1_dom.
DR PANTHER; PTHR13780; AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR13780:SF125; MEIOTICALLY UP-REGULATED GENE 70 PROTEIN; 1.
DR Pfam; PF00571; CBS; 4.
DR Pfam; PF00564; PB1; 1.
DR SMART; SM00116; CBS; 4.
DR SMART; SM00666; PB1; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 2.
DR PROSITE; PS51371; CBS; 4.
DR PROSITE; PS51745; PB1; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000091918};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 648..667
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 98..159
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 165..221
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 268..325
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 334..391
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 475..576
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT REGION 1..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 413..476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 576..627
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..78
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..608
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 611..625
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 673 AA; 72659 MW; 4DF72661552C20B0 CRC64;
MSAAGGGTFR NRTVGRGQLP FDGSPSGIPR KVDQGPPPAA TPSDIGSSSA LSTSRQKQSK
RDEAIRKKME ADLNKKRHGN PARSRHSRKA PPGTVMALKP SQALQIKPNT TVAEAAQLMA
AKREDCVLVT DDDDRIAGIF TAKDLAFRVV GAGIRARDVT IAEIMTKNPL CARTDTSATD
ALDLMVRKGF RHLPVMDENQ DISGILDITK CFYDAMEKLE RAYSSSRKLY DALEGVQSEL
GSNQPQQIIQ YVEALRQKMS GPTLESVLSG LPPTTVSVRT SVREAAALMK ENHTTALLVQ
DQGSITGIFT SKDVVLRVIA PGLDPNTCSV VRVMTPHPDF APTDMSIQAA LRKMHDGHYL
NLPVMNEAGE IVGMVDVLKL TYATLEQVNS MATNENEGPA WNKFWLSMDH ESDSMVSGSH
GHSQHLHTPH RSVMSPDISR AHGDRENSVL PNESASHHGD EAASEVLGPR PAHEDTPFPF
KFKAPSGRVH RLHVTPSAGV ADLVAQVSLK LGAEVEAVGG SAVVEDGKIS HLGYALSYMD
SEGDTVSITT DQDLWDAINL ARRANRDKVD LFVHDPEKQP VVGPPPPYPP APEPQPTVSK
PVTPPEPVPR TVASEDDELS NVEREKTQTL FRPPSAEQQL INGVPNELIL PGAIVTLAVA
IVGVFVLSRA GNR
//
