ID A0A1B7P6P1_9EURO Unreviewed; 1008 AA.
AC A0A1B7P6P1;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN ORFNames=ACJ72_00934 {ECO:0000313|EMBL:OAX84692.1};
OS Emergomyces africanus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emergomyces.
OX NCBI_TaxID=1955775 {ECO:0000313|EMBL:OAX84692.1, ECO:0000313|Proteomes:UP000091918};
RN [1] {ECO:0000313|EMBL:OAX84692.1, ECO:0000313|Proteomes:UP000091918}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 136260 {ECO:0000313|EMBL:OAX84692.1,
RC ECO:0000313|Proteomes:UP000091918};
RA Cuomo C.A., Schwartz I.S., Kenyon C., de Hoog G.S., Govender N.P.,
RA Botha A., Moreno L., de Vries M., Munoz J.F., Stielow J.B.;
RT "Emmonsia species relationships and genome sequence.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAX84692.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LGUA01000056; OAX84692.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B7P6P1; -.
DR STRING; 1658172.A0A1B7P6P1; -.
DR OrthoDB; 1362946at2759; -.
DR Proteomes; UP000091918; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR PANTHER; PTHR31323; MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2; 1.
DR PANTHER; PTHR31323:SF1; MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000091918};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 133..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 483..504
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 516..542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 431..466
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 717..1008
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..88
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 725..759
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 821..837
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 881..896
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 932..946
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 963..981
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1008 AA; 111300 MW; 5FA5834F1663A79C CRC64;
MRDRPGIGQK RFSRDRFQRL EEGSHYQETT TTMNSNDATV NIPLTNVPSR DQTGSRKVNS
NGSSSSYTPP TDLPAEHDHD DNEKNGIFHH RKGGRRMLSS HGKRQLEGLE DGTLTRMGKF
YNAILNFSVV TRYFIYVSPL ALLIAIPIVV GATVAQNAEI GGVRIVWFFT WVEIVWLSLW
VSKVIAHYIP FVFQFLCGIV SSGTRKYALL LRALEIPFSL IGWSVTSLAT FIPLMTRNPT
KRASGNTGIQ HWQNVVKNIL FAAFISTLIL FVEKLLVQLI SISYHRRQFD NRIKESKRNI
SLLVMLYEAS RTLFPEYCAE FEEEDYVISD SIVRVVKFTR GHKRVGSASP MRLIHGVGRV
GDKLTAAFGN VAQEITGKQV FNSTSAHSVV TLALEKRKSS EALARRLWMS FVLQGRESLY
LDDVIEVLGA GREEEAKECF GMLDLDSNGD VSLEEMILTV TEIGRVQKSI NNSMHDVDQA
IHVLDNLLCA VVFIMVVLVF VAFLNTGFGT TLAAGATALL SLSFVFATTA QEVLGSTIFL
FVKHAMDVGD RVDIGDRQLI VERISLLYTV FRGVRDHKTF QAPNIVLNTQ WIENVTRSRA
MREQITLTVD FGTSFADIQL LKAEMQKFVR DKENARDFQP DVDIEVVGLG SMDKLELKIE
IRHKSNWSNE TVRATRRSKF MCALVLAVRK IPIHGPGGGD AVLGDIMRPS YSVAISQEQA
QASQEEWSKG KEGKRMVPTS EMDEYFDTTK HKDDVEGRST AVEGMSPTGS PVHRGASTRS
PPAKDTDMET SVVKALHTRP PAMDQARVDE SEILRQSDTG AGAGETGSRT SNPSNRDGLP
PHREPSTGRR TGAPVARYVS PNTPIDEAVP TQVVPTRSAP PLSAPGFPPP AQHQPPTARS
TPEYFELTQR DPSGAAAGRE NPHYPSSNTN NPYVPRPSPP PLAHQMPPQS AAAYGGGSSG
NPPMGSGPGT LQQTQATPSR RLAPGGNAFA LHSQSEQQYP EQPQPPRR
//
