ID   A0A1B7P864_9EURO        Unreviewed;       357 AA.
AC   A0A1B7P864;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=CMP/dCMP-type deaminase domain-containing protein {ECO:0000259|PROSITE:PS51747};
GN   ORFNames=ACJ72_00430 {ECO:0000313|EMBL:OAX85201.1};
OS   Emergomyces africanus.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emergomyces.
OX   NCBI_TaxID=1955775 {ECO:0000313|EMBL:OAX85201.1, ECO:0000313|Proteomes:UP000091918};
RN   [1] {ECO:0000313|EMBL:OAX85201.1, ECO:0000313|Proteomes:UP000091918}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 136260 {ECO:0000313|EMBL:OAX85201.1,
RC   ECO:0000313|Proteomes:UP000091918};
RA   Cuomo C.A., Schwartz I.S., Kenyon C., de Hoog G.S., Govender N.P.,
RA   Botha A., Moreno L., de Vries M., Munoz J.F., Stielow J.B.;
RT   "Emmonsia species relationships and genome sequence.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the cytidine and deoxycytidylate deaminase
CC       family. {ECO:0000256|ARBA:ARBA00006576}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAX85201.1}.
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DR   EMBL; LGUA01000022; OAX85201.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1B7P864; -.
DR   STRING; 1658172.A0A1B7P864; -.
DR   OrthoDB; 178124at2759; -.
DR   Proteomes; UP000091918; Unassembled WGS sequence.
DR   GO; GO:0019239; F:deaminase activity; IEA:UniProt.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd01286; deoxycytidylate_deaminase; 1.
DR   Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR016192; APOBEC/CMP_deaminase_Zn-bd.
DR   InterPro; IPR002125; CMP_dCMP_dom.
DR   InterPro; IPR016193; Cytidine_deaminase-like.
DR   InterPro; IPR015517; dCMP_deaminase-rel.
DR   InterPro; IPR035105; Deoxycytidylate_deaminase_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11086:SF18; CYTIDINE AND DCMP DEAMINASE DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR   PANTHER; PTHR11086; DEOXYCYTIDYLATE DEAMINASE-RELATED; 1.
DR   Pfam; PF00383; dCMP_cyt_deam_1; 1.
DR   SUPFAM; SSF53927; Cytidine deaminase-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00903; CYT_DCMP_DEAMINASES_1; 1.
DR   PROSITE; PS51747; CYT_DCMP_DEAMINASES_2; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000091918};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          185..323
FT                   /note="CMP/dCMP-type deaminase"
FT                   /evidence="ECO:0000259|PROSITE:PS51747"
SQ   SEQUENCE   357 AA;  40345 MW;  3106EAD813EACE8F CRC64;
     MLLGLCGGIC SGKHSVAEYL IQKHGFQQLQ LAQRPDHLHE ATELPPSFGN HTPINGSQVF
     QTVEELLDFV TKRWQDRWVT TDIWDEATLE RLLMRPYFLL VSVDAPVSLR WSRFTERSWR
     RQLDPPDLEK FVLWNDKHLY DKDTGIAYMT DRAQVRLFNS SSSLHELHSA LEELDLANEQ
     RLRPGWDQYF MQLASLAAQR SNCMKRRVGC VLVRGKRVMS TGYNGTPRNT KNCNEGGCPR
     CNYGHGGGAA LSTCLCIHAE ENALLEAGRE RIGEGSILYC NTCPCLTCSV KIAQLGISEV
     VYSQSYSMDK ETASILEEAG VKLRQFSPPR NGLVYLQKSD ILISTDHEAF NSEPTII
//