ID A0A1B7TB22_9ASCO Unreviewed; 1015 AA.
AC A0A1B7TB22;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OBA25946.1};
GN ORFNames=HANVADRAFT_49600 {ECO:0000313|EMBL:OBA25946.1};
OS Hanseniaspora valbyensis NRRL Y-1626.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycodaceae; Hanseniaspora.
OX NCBI_TaxID=766949 {ECO:0000313|EMBL:OBA25946.1, ECO:0000313|Proteomes:UP000092321};
RN [1] {ECO:0000313|Proteomes:UP000092321}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-1626 {ECO:0000313|Proteomes:UP000092321};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
CC -!- SIMILARITY: Belongs to the NEMF family.
CC {ECO:0000256|ARBA:ARBA00008318}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBA25946.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LXPE01000032; OBA25946.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B7TB22; -.
DR OrthoDB; 129892at2759; -.
DR Proteomes; UP000092321; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0072344; P:rescue of stalled ribosome; IEA:UniProt.
DR Gene3D; 2.30.310.10; ibrinogen binding protein from staphylococcus aureus domain; 1.
DR InterPro; IPR021846; NFACT-C.
DR InterPro; IPR008532; NFACT_RNA-bd.
DR PANTHER; PTHR15239; NUCLEAR EXPORT MEDIATOR FACTOR NEMF; 1.
DR PANTHER; PTHR15239:SF6; RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF; 1.
DR Pfam; PF11923; NFACT-C; 1.
DR Pfam; PF05670; NFACT-R_1; 1.
DR Pfam; PF05833; NFACT_N; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000092321}.
FT DOMAIN 592..689
FT /note="NFACT RNA-binding"
FT /evidence="ECO:0000259|Pfam:PF05670"
FT DOMAIN 901..988
FT /note="NFACT protein C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11923"
FT REGION 464..509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 767..798
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 810..852
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 992..1015
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 355..382
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 464..498
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 772..793
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 822..852
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1015 AA; 117010 MW; 744C0E88F2D5F6F3 CRC64;
MKEKLTALDL EVSVNELEQN LVGLRLNNIY NVQDNNKQFL LKFQKPNVKQ NFIIDCGLKL
YITKFSRNTP TTPSGFIVKL RHFLSNKKLT GLKKVSNERI IVLQFSNGMF YLSLEFFSSG
NLLVLDENLK ILQVFRVNEE HNVKIGQYYN LFNPLELFDE ENKTSNNINN LVSSYLATDL
NNINEKYLTN VFKQEQEKIS KSENINNKKF KVLSISKLLY LNYPTLTNQL IQDKLKTAGF
KPNETCANFF DADETTIQSF LKVLKDCVFE VKSVLETDTS KRVGYLTKIN NPTFLESEEE
NDETNPRFLY DSYSPFKPSG DSTANDFDEV TGGYIFAIDK FYSTLELLKT STKTNNFISQ
QNKKLEQTKM ENEKRVQQLD EVSVSNEIKG NTIISNIEIV EELIEIIKTL TIKNQMDWKA
IELWIQNQQK KKKATDPIQN IKFPLNLEEN KLNIVLPIDR FDNDEEEEEV SSSDSDSSSD
SDSSDSDSDS DNDSDSDDDD FKVNSSQKQK KPKKEVKKIS IWIDFTLSAY TNASNYFQVK
KELQTKKTKT LANQQKAMKS IEHKFNKNLN KKLQKETQPL ITKLREPFFF QKFNWFLTTD
GYLAILLNDD MIYWKYAEPN DFYLNSNNTI SSKNSQVLIK NLRNEDTLSE RAIVEVSQFS
LAGSEAWSKK ISSASCYYCK IDNISKFAND DFKKNGVLDN AKFYIKDESK LINLSPVQLV
MGFGLLWRKK LKDSNVEYIE QAEENSISAA PTDEEIKQVM EQIDSTVDDE ISIADSENKD
LNSKEESGET SMTSGRESHK SVIANALEEF DELSNRSPAR SSNKETKNKN KQKKESTPDT
ANKISDDSVK RLERSQQLKE KAMYQTMKIT KLMNTPKPKV HYELMLKELS PVMKLSNDEK
DDLLYDYELV PMFAPWMALS KTKFKVKIQN GTNKKLKNCN DIMIYFENHL KIDNESKDKE
CIWPKELELI RDYPTEGLVT SFFIDKFKCT LPGSKGESNG GNKSSKKNKG NKKKK
//
