ID   A0A1B7VWY5_APHFL        Unreviewed;       340 AA.
AC   A0A1B7VWY5;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:OBQ25475.1};
GN   ORFNames=AN481_09900 {ECO:0000313|EMBL:OBQ25475.1};
OS   Aphanizomenon flos-aquae LD13.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Aphanizomenonaceae;
OC   Aphanizomenon.
OX   NCBI_TaxID=1710894 {ECO:0000313|EMBL:OBQ25475.1, ECO:0000313|Proteomes:UP000092382};
RN   [1] {ECO:0000313|EMBL:OBQ25475.1, ECO:0000313|Proteomes:UP000092382}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MDT13 {ECO:0000313|EMBL:OBQ25475.1};
RA   Driscoll C.;
RT   "Whole genome shotgun sequence assembly of Aphanizomenon flos-aquae
RT   UKL13.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC       subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OBQ25475.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LJOY01000028; OBQ25475.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1B7VWY5; -.
DR   STRING; 1803587.GCA_001593825_03182; -.
DR   PATRIC; fig|1710894.3.peg.4038; -.
DR   Proteomes; UP000092382; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd03112; CobW-like; 1.
DR   Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR036627; CobW-likC_sf.
DR   InterPro; IPR011629; CobW-like_C.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR13748:SF65; 47 KD PROTEIN; 1.
DR   PANTHER; PTHR13748; COBW-RELATED; 1.
DR   Pfam; PF02492; cobW; 1.
DR   Pfam; PF07683; CobW_C; 1.
DR   SMART; SM00833; CobW_C; 1.
DR   SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          251..339
FT                   /note="CobW C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00833"
SQ   SEQUENCE   340 AA;  38752 MW;  D93A371C10676A40 CRC64;
     MNTITLNTTN TIPEIPKRGM PITIITGFLG SGKTTLLNQI LQNKQDLKVA VLVNEFGDIN
     IDSQLLISVD EAMMELSNGC ICCTINDGLV DAVYRVLERE DPIDYLVIET TGVADPLPII
     LTFFSTELRD LTNIDSILTV VDAEAFDEEH FQSEAALKQI TYGDIILLNK TDLVTPEKIQ
     EVENFIHDIK HGAKILHTQY GEVALPLILD VGLTPKDKYI AIDDEDTHKH EHHHEHEHHH
     HHSDHLDNDG FVSISFQSDK PFDVHKFENF LTEEMPENVF RAKGILWFSD SELRHIFQLS
     GHRYTLNADE WYNSPKNQVV FVGRKLDTNE IYTKLNKCLL
//