ID A0A1B7ZFW8_9FLAO Unreviewed; 860 AA.
AC A0A1B7ZFW8;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=DNA mismatch repair protein MutS {ECO:0000256|HAMAP-Rule:MF_00096};
GN Name=mutS {ECO:0000256|HAMAP-Rule:MF_00096};
GN ORFNames=A9200_02915 {ECO:0000313|EMBL:OBR42422.1};
OS Maribacter hydrothermalis.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Maribacter.
OX NCBI_TaxID=1836467 {ECO:0000313|EMBL:OBR42422.1, ECO:0000313|Proteomes:UP000092164};
RN [1] {ECO:0000313|Proteomes:UP000092164}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T28 {ECO:0000313|Proteomes:UP000092164};
RA Zhan P.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein is involved in the repair of mismatches in DNA.
CC It is possible that it carries out the mismatch recognition step. This
CC protein has a weak ATPase activity. {ECO:0000256|HAMAP-Rule:MF_00096}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|HAMAP-Rule:MF_00096,
CC ECO:0000256|RuleBase:RU003756}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBR42422.1}.
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DR EMBL; LZFP01000001; OBR42422.1; -; Genomic_DNA.
DR RefSeq; WP_068481881.1; NZ_LZFP01000001.1.
DR AlphaFoldDB; A0A1B7ZFW8; -.
DR STRING; 1836467.BTR34_11300; -.
DR KEGG; mart:BTR34_11300; -.
DR OrthoDB; 9802448at2; -.
DR Proteomes; UP000092164; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:UniProtKB-UniRule.
DR CDD; cd03284; ABC_MutS1; 1.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00096; MutS; 1.
DR InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01070; mutS1; 1.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00096}; Reference proteome {ECO:0000313|Proteomes:UP000092164}.
FT DOMAIN 680..696
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT BINDING 606..613
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00096"
SQ SEQUENCE 860 AA; 97196 MW; E5EAC2AB0DD126B3 CRC64;
MKQYNTIKTK YPDALLLFRV GDFYETFGED AVKASRILGI ILTNRNNGGE RTELAGFPHH
SLNTYLPKLV KAGQRVAICD QLEDPKQTKT IVKRGVTELV TPGVAMNDDI LNSKTNNFLC
AVHFGRKKIG IAFVDISTGE FLTSEGSEEQ IDKLLQNFSP NEILISKAHK KEFTEVFGKN
HHLFYLEDWV FQEDYALENL TSHFNTNTLK GFGVDHLTCG IIASGVVLHY LGETQHRQLQ
HISKLQRIAE DDYIWMDRFT IKNLELYHST NVNAVTLLDI IDKTISPMGG RMIKRWLALP
LKNLEKIKRR QQIVSFLHDE EVVLEKFQHH IKQMGDLERL ISKVATGKVN PKEVVQLKNS
LEALIPIKQL ATSSKNESLA LTGDQIQSCD LLRAKIKEML SEEAPVNILK GSTIAKGFSE
ELDELRGLAK SGKNYLNNML ERETAATGIT SLKIASNNVF GYYIEVRNTH KDKVPETWTR
KQTLVNAERY ITEELKEYEA KILGAEDRIS TLEQQLFSQL VVWMQEYIAP VQNNAFLIAQ
LDCLCGFAQL AKENSYNCPE LNDSTDLELK DGRHPVIEKQ LPLGEQYIAN DLQLDRSNQQ
FIMITGPNMS GKSALLRQTA LIVLLAQMGS FVPAETAKIG VIDKIFTRVG ASDNISMGES
TFMVEMNETA SILNNLSERS LVLLDEIGRG TSTYDGISIA WAISEYLHEH PARAKTMFAT
HYHELNEMTN TFNRIKNFNV AIKELKDTVL FLRKLVPGGS EHSFGIHVAK MAGMPQQVIQ
KANKILKKLE NKHVSEEIGN QLKSTSDEMQ LSFFNLDDPL LEEIKEEITH LDIDTLTPVE
ALMKLNEIKR LLTKDKKATS
//
