ID A0A1B8ATJ0_FUSPO Unreviewed; 1271 AA.
AC A0A1B8ATJ0;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Rho1 guanine nucleotide exchange factor 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=FPOA_04239 {ECO:0000313|EMBL:OBS23691.1};
OS Fusarium poae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=36050 {ECO:0000313|EMBL:OBS23691.1, ECO:0000313|Proteomes:UP000091967};
RN [1] {ECO:0000313|EMBL:OBS23691.1, ECO:0000313|Proteomes:UP000091967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2516 {ECO:0000313|EMBL:OBS23691.1,
RC ECO:0000313|Proteomes:UP000091967};
RA Vanheule A., Audenaert K., Warris S., Van De Geest H., Schijlen E.,
RA Hofte M., De Saeger S., Haesaert G., Waalwijk C., Van Der Lee T.;
RT "Living apart together: crosstalk between the core and supernumerary
RT genomes in a fungal plant pathogen.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS23691.1}.
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DR EMBL; LYXU01000002; OBS23691.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8ATJ0; -.
DR STRING; 36050.A0A1B8ATJ0; -.
DR OMA; CFRQKII; -.
DR Proteomes; UP000091967; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd04435; DEP_fRom2; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001180; CNH_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041675; PH_5.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46572; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46572:SF2; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR Pfam; PF00780; CNH; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF15405; PH_5; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00036; CNH; 1.
DR SMART; SM00049; DEP; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50219; CNH; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000091967}.
FT DOMAIN 401..476
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 572..763
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 708..926
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 948..1241
FT /note="CNH"
FT /evidence="ECO:0000259|PROSITE:PS50219"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 35..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 309..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 352..384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 127..167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..195
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..338
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..369
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1271 AA; 143554 MW; AF565B1467504EA1 CRC64;
MHGEDRDIRS AVDTSDIELP ASGAHATVVS AAMSNYGYDP RGAPQRPPQR GYGDDNYGQR
DAAFSNIFGA APPPGRSQTM TSSSSMPQSM MDPGRTQTMS SMSSGMQRQP PPRAPPGHYG
DHPNAGRTRT MDSNSMMGNG YYPSQRSASG GQQMPPHYMQ QQQQARRPYP GPGPGGPAPP
RMDPRGPPPQ QAPGPRTPAQ RFYQGGPGPG PAMNNDPYRS QSLASAPRQP MYHPPPSTYQ
QAPANHLRQA PYAQQNSSRT TAQGRVVPER HEDRTMSLTG NYQPQSMDAH QTMSGRVIPN
RRAPAELPTA NGYPNSMPHA PGAQTRTSSM VSSNGGGDHG RTMSMASTIA PTITPSESDA
STLAQRPTRS KSIESERPPT ATKIRPPLVY PALLSRVGEC FRKKIIVGDR TKNELTYKNA
FSGSEAVDVL SYIIRTTDRN LALLLGRALD AQKYFHDVTY EHRLRDSQSE MYQFRETLMD
EPEDKPAVNG VFVLLSECYS PTCTRDQLCY SIACPRRLEQ VSRLNLKINP GLRKEDAVNA
VDDEVDQTDE QKLWINSVPK EVAEKVGDKE KKRQEVISEI CYTERDFVKD LEYLRDFWIL
PLRSKASPVP VQRREKVVKT IFSNIIDHPS IHTVSSRFAS NLTTRQQKEP IVHNIGDIFL
EYVPQFEPFI LYGSKQLEGK FEFENERSVN PYFGKFVDEI ERRKESRKLE LNGYLTKPTT
RLARYPLLLE NVLKYTEDDN PDKEDIPKVL VMIRDILGRV NAESGKAENR FNLRRLHEQL
RFRPNERVDL RLTEEGREMV FKCQFKKTAT DPPEITAFLF DHAVLLVRIK QTGKAEEIKA
YRRPIPLELL AIKEMDEVIQ KDGNMKRTSS SLIPSIRNNT NNDPARKEGW PITFRHLGKA
GYELTLFASN QATRQKWLEF IHTAQERLRS RADFFNTTVI SSHFFAGTNR VNCVTPFDGG
RKLLYGTDSG VYLSDRKVKD QVPRRVLETA SVTQIDILEE YQLLLVLSNK TLQSYPVSAL
NPDEPALSRR PKKIQSHCSF FKTGICLGRH LVCCVKSSAL STTIKVFEPN DAMTKAKKQK
GIGKFMSGGH DELKPFKEFY IPTESSSVHF LKSKLCVACA RGFEVVSLET LETQSLLDQA
DTSLDFVARK EGVKPIHIER LNGEFLLNYS EFSFFVNRNG WRARPEWRID WEGTPQSFAL
SYPWILAFEP NFIELRNMEN GAVHIVPRKN IRMLHSSTHE ILFAHEDEKG DDIVEAIDFW
KSNRKSELLG S
//
