ID A0A1B8C3S4_9PEZI Unreviewed; 640 AA.
AC A0A1B8C3S4;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Exocyst complex protein EXO70 {ECO:0000256|RuleBase:RU365026};
GN ORFNames=VE00_08054 {ECO:0000313|EMBL:OBT41430.1};
OS Pseudogymnoascus sp. WSF 3629.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1622147 {ECO:0000313|EMBL:OBT41430.1, ECO:0000313|Proteomes:UP000091997};
RN [1] {ECO:0000313|EMBL:OBT41430.1, ECO:0000313|Proteomes:UP000091997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSF 3629 {ECO:0000313|EMBL:OBT41430.1,
RC ECO:0000313|Proteomes:UP000091997};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000091997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSF 3629 {ECO:0000313|Proteomes:UP000091997};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC -!- FUNCTION: Involved in the secretory pathway as part of the exocyst
CC complex which tethers secretory vesicles to the sites of exocytosis.
CC Also plays a role in the assembly of the exocyst.
CC {ECO:0000256|RuleBase:RU365026}.
CC -!- SUBCELLULAR LOCATION: Bud {ECO:0000256|RuleBase:RU365026}. Bud neck
CC {ECO:0000256|RuleBase:RU365026}.
CC -!- SIMILARITY: Belongs to the EXO70 family.
CC {ECO:0000256|ARBA:ARBA00006756, ECO:0000256|RuleBase:RU365026}.
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DR EMBL; KV454658; OBT41430.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8C3S4; -.
DR STRING; 1622147.A0A1B8C3S4; -.
DR OrthoDB; 460764at2759; -.
DR Proteomes; UP000091997; Unassembled WGS sequence.
DR GO; GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.
DR GO; GO:0000145; C:exocyst; IEA:InterPro.
DR GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:InterPro.
DR GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1280.170; Exocyst complex component Exo70; 1.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR004140; Exo70.
DR InterPro; IPR046364; Exo70_C.
DR PANTHER; PTHR12542:SF41; EXOCYST COMPLEX COMPONENT 7; 1.
DR PANTHER; PTHR12542; EXOCYST COMPLEX PROTEIN EXO70; 1.
DR Pfam; PF03081; Exo70_C; 1.
DR Pfam; PF20669; Exo70_N; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
PE 3: Inferred from homology;
KW Exocytosis {ECO:0000256|ARBA:ARBA00022483, ECO:0000256|RuleBase:RU365026};
KW Protein transport {ECO:0000256|RuleBase:RU365026};
KW Reference proteome {ECO:0000313|Proteomes:UP000091997};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365026}.
FT DOMAIN 247..634
FT /note="Exocyst complex subunit Exo70 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03081"
FT REGION 529..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 640 AA; 69938 MW; 6C3E6CEA4E6ED37B CRC64;
MAITPSARQA ADEEARAEVD VLTSRLEKTA QLTKKIQASL TRLETSGRSV QEAIGPIYGN
TQRLQVLGNN IDSILSAIET VRGPSDIKNN EEEIIRSGPD NAGLSSYLAS MNRVTRALSD
LKSTNMKSNQ QALSDLSRLI QFGNQQLESV FRRILQEDAA PVEPLNFITK QKPWPTLSQD
KTTRLGLINS FVGARQQTSM VSQESPTAKI YANVRGPYLQ ASLANLAAAS VNTAKKKSAD
AIYKHGTNGI GMYAQAIEGA YIAEHENVCA LFARDDWGRV FNLTCQGAMD DVGRTLRELN
VHIRAHLTTD CFLAYEILEI ISQLSSRVET QTGELKGPFG SVLKPIRDTA RSSLAELIDD
TRKRVTGIQS IPVDVPPLPI TTETMARLQT MVEFLRPISG IMISLGDGNW KSVSGANPSA
DATPSLASFD VTADGKELFA HYSADTVDTL LSSLQAKGAQ LLKTKQLQGV FLANNLVVVN
RMIGASDLAP LLKSRIPSLD TWKKKATSLY MDPWLETSRI LMDVVHTGGS RTGGGRAGRP
ASGSTGNESA AVVKALSSKE RDIIKEKFRQ FNATFDELVA KHKTLTMEKE VREAFARDVQ
AMVEPLYGRF WDRYHELDRG RGKYVKYDRG AVAAICAGLA
//
