ID A0A1B8C6L9_9PEZI Unreviewed; 664 AA.
AC A0A1B8C6L9;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN ORFNames=VE00_07936 {ECO:0000313|EMBL:OBT42465.1};
OS Pseudogymnoascus sp. WSF 3629.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1622147 {ECO:0000313|EMBL:OBT42465.1, ECO:0000313|Proteomes:UP000091997};
RN [1] {ECO:0000313|EMBL:OBT42465.1, ECO:0000313|Proteomes:UP000091997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSF 3629 {ECO:0000313|EMBL:OBT42465.1,
RC ECO:0000313|Proteomes:UP000091997};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000091997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSF 3629 {ECO:0000313|Proteomes:UP000091997};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC in alpha-L-rhamnosides.; EC=3.2.1.40;
CC Evidence={ECO:0000256|ARBA:ARBA00001445};
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DR EMBL; KV454637; OBT42465.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8C6L9; -.
DR STRING; 1622147.A0A1B8C6L9; -.
DR OrthoDB; 67137at2759; -.
DR Proteomes; UP000091997; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR035396; Bac_rhamnosid6H.
DR InterPro; IPR035398; Bac_rhamnosid_C.
DR PANTHER; PTHR34987:SF4; ALPHA-L-RHAMNOSIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR34987; C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED; 1.
DR Pfam; PF17389; Bac_rhamnosid6H; 1.
DR Pfam; PF17390; Bac_rhamnosid_C; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000091997}.
FT DOMAIN 234..461
FT /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT /evidence="ECO:0000259|Pfam:PF17389"
FT DOMAIN 572..632
FT /note="Alpha-L-rhamnosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF17390"
SQ SEQUENCE 664 AA; 71418 MW; 4E9297D42184EB5F CRC64;
MRFSSLPQGA LSTIIFSGCV SAVKFQEYIL APSDRNVQCR DLLNTTNKVE NPGALCTASE
NSDGTTFTGN SAITIDFGKN VAGTVQFNVK SVSGDAEFIG FTFTESNMWI STTLSDSANA
ATFDSPLWFP VGAAGAYAAD KTHQRGGFRY MSLWHNSTGE MVIDLLSVNF TASPEMANAQ
DYAGYFNSDS EKLNRVWYAG AYTNQLCTSD PVYGNSQNVP GVDWYLTGRL SEGTSVLMDG
AKRDRLVWPG DIAISGPSMF VSTNSLDGIK NGLSALFSMQ EAGGRLPYNG IGYFLKGHFD
YSFTYHLYTL LDLYDYYTYS GDLAYLKKYW PQYKRGLANT VALIDSTGMA KVDSPNDWLR
SGMGGHNGEA NSIFYHTLEK SITLASVLND TALIPTWTAA MSSIRAALNA NLWDPSKNLF
FDNAEDKSAT AVHPQDGNSW AIIAGLVTPD RASAISKALA DRWVRPFGAP APEAGKAISP
FASGFEVQAH YLAGAAHRAI DLMEFMWADF MLDDPRMTNS SLIEGYSADG SLHYPPYDND
ARVSHAHGWA TGPTSALSFF GAGIQLSSAM GRTWEIHPRL GGLKRISAGY ETGLGKFEAE
WAASGKVVVG SFTTPQGTSG KLVLPGGEGL TVTGLNGVVA PTKKGSDTFV YADLPGGTYE
IALA
//
