ID   A0A1B8C6X7_9PEZI        Unreviewed;      1044 AA.
AC   A0A1B8C6X7;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   13-SEP-2023, entry version 23.
DE   RecName: Full=Tuberous sclerosis 1 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=VE00_07144 {ECO:0000313|EMBL:OBT42592.1};
OS   Pseudogymnoascus sp. WSF 3629.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1622147 {ECO:0000313|EMBL:OBT42592.1, ECO:0000313|Proteomes:UP000091997};
RN   [1] {ECO:0000313|EMBL:OBT42592.1, ECO:0000313|Proteomes:UP000091997}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSF 3629 {ECO:0000313|EMBL:OBT42592.1,
RC   ECO:0000313|Proteomes:UP000091997};
RA   Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT   "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT   white-nose syndrome of bats.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000091997}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSF 3629 {ECO:0000313|Proteomes:UP000091997};
RX   PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA   Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT   "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT   white-nose syndrome of bats.";
RL   Nat. Commun. 9:35-35(2018).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KV454635; OBT42592.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1B8C6X7; -.
DR   STRING; 1622147.A0A1B8C6X7; -.
DR   OrthoDB; 1430252at2759; -.
DR   Proteomes; UP000091997; Unassembled WGS sequence.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR007483; Hamartin.
DR   PANTHER; PTHR15154; HAMARTIN; 1.
DR   PANTHER; PTHR15154:SF2; HAMARTIN; 1.
DR   Pfam; PF04388; Hamartin; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000091997}.
FT   REGION          292..312
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          431..450
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          497..525
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          539..567
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          874..1044
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          708..804
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        434..450
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        886..916
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        924..964
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        994..1033
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1044 AA;  118207 MW;  8A8AB36BBB190686 CRC64;
     MSSGSLKDVV KSIHSQVSSG VLPLSNDLID HIQAYLDKHL PIEDGDSQKL QEELLSIWQK
     QALDNPDRYS IFIAILRELI PAIRSAAQWL QWWEMFVVPV LGNIGDGKGL ARETRQLLLD
     VLLFEADDGD SARIEAVRET CTMLSDKVLG VWLNQSRVAT TEADAMAHYL DQQIKTLLLA
     FGQKRPQVLL TAIDKYFVKR EHRGQVLSLL SEFIRHGPPH LHLLLQTPLF DNLLRCLQID
     TSTTVVALAM TALTMILPHI PVSTGKHLPS LFNIYTRMLF WERERALSPR LRLDSNEQND
     NSESSEKGQE EKVPWEKLSY SFQSDDETLP ELLHYFTFLY GLYPINFMSY IRKPSRYLRH
     ANFPGADDID VEPNEIRKRS EPFRELHLLH PNFFSLTIES ELTDAHRWMN SAASDVVTFC
     MSLCVPVYHG SSSAPPMTRF SSLPNRDSNQ DIPAQTLLTQ TDSEEALIAQ RHSHETPSSG
     GGPPELSALA RLSLRTNPSV SSDVHMATNV TQDIRSDSPT IPNQRRMSPL HDILNSQQSL
     HRGLHQSLPN ESSTTLSSVG GNTDSSANVD TYLQSLAQLP PRSPSLRPSL GDTTNMAFLR
     REIMLLRNDL NFERYLKQQH LSHIGQLRRM QVREATVEAE TQNLINANKI LKGKLEEAKN
     LTTQTKKESD KSRAQSKKWE QDLSAKLRAI KDEQKRWILE GDLLRRALQE SQENGEELKQ
     LVIKSEAREM ESSRKLQAIK IELDDLAKLR SDVDRLTEHL REFQNQESEM EDVKAREDIA
     NSKIELLNMQ LKAREEELLK TKRANAAEIQ DLKLHMKDVA QNAHSTATQN FKIMLDSALA
     ASKLRLAEVH KAHTHLLRRY TSLQEDYLRL QEQHSTPGPL LGDSDEIESL ESRSPTDTRN
     MPHRQPRRDS EDPQRLGHGG ADNGSRQRSF SPDEQRKMSA ATGSMMIPTR TGSSTHSDPR
     SLFNGGSLDN GAEAEMPKPK PQRRAYGRGG VQNSGLKERK EKEKREKERR ESEAESLSQS
     PTHNKKDKKG GPGGFKSIKG LVSM
//