ID A0A1B8CF20_9PEZI Unreviewed; 722 AA.
AC A0A1B8CF20;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=RGS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=VE00_04590 {ECO:0000313|EMBL:OBT45437.1};
OS Pseudogymnoascus sp. WSF 3629.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1622147 {ECO:0000313|EMBL:OBT45437.1, ECO:0000313|Proteomes:UP000091997};
RN [1] {ECO:0000313|EMBL:OBT45437.1, ECO:0000313|Proteomes:UP000091997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSF 3629 {ECO:0000313|EMBL:OBT45437.1,
RC ECO:0000313|Proteomes:UP000091997};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000091997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSF 3629 {ECO:0000313|Proteomes:UP000091997};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
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DR EMBL; KV454594; OBT45437.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8CF20; -.
DR STRING; 1622147.A0A1B8CF20; -.
DR OrthoDB; 1364107at2759; -.
DR Proteomes; UP000091997; Unassembled WGS sequence.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR CDD; cd04450; DEP_RGS7-like; 1.
DR CDD; cd08708; RGS_FLBA; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10845; REGULATOR OF G PROTEIN SIGNALING; 1.
DR PANTHER; PTHR10845:SF192; RGS DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00049; DEP; 2.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000091997};
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700}.
FT DOMAIN 439..508
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 544..694
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT REGION 1..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 701..722
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..131
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..190
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 722 AA; 80676 MW; 94D0D3FC15CA095A CRC64;
MALTKSSHPE HHLPTLSRSD FPEQPQFFQD SPDSLATSSL TGSQPSPEKN PSIDSLLRVR
SNSKHRQSTL STTSSRSSRT NLLTFAALAR DKTTSAIANF SDPVTRAQVS RKNSHNRRTA
GDSEKSPERI SDPSRSIIPQ AKESQSITTP RPGLQDTEPP SQSYEDTDAN TPTPRKVGAP
EQSTMHQTSS RLLRMTEDDR PFTRVSDESP ESYLFSTARA NYLHRYQDFK DLFATLIVSL
PLESHRRMFN KCEHSFLSEE AINNLGSLKF SQSNRMPDPK DPSRIVTTTT TTTFSMARDM
ARTVCQRFVD ARFIESADGK QIREFNLKGT LWQLTPKGIH VLDRFCSKNG IQQRHVVDLV
NSPKNTMQLV VLERDSVTDE ISQDRGTVEV LFRRFIGANG PNVKSSVSAA DSDSLSEYKD
GLAGVRMAGE RKIGSPQRTV LQSFTGKAAV DWLLDCCTTV DKNETMKIAA LFLEHDLLWC
VLSDRSYTSQ FPAHKFQPTK IAIYQMTQKG KDVINMSSTH RLSNGDVDSP SSRVGVSRDS
NTQKLDKILT DAALRLLFRE QLRDTHCEEN LSFYLDVDEF LKSCSDALQG MSPSSRAKNP
DRSLDAIKET MASAYGIYNA FLAPGSPCEL NIDHLLRSQL ASRMTKAVGR DDAMIESLKE
VIKLFEEAQL SVFKLMASDS VPKFMKSAKY EQTLKNYDFD SIPAHPAPGQ PRSHGSVNRS
SR
//
