ID A0A1B8CG62_9PEZI Unreviewed; 1438 AA.
AC A0A1B8CG62;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Rab-GAP TBC domain-containing protein {ECO:0000259|PROSITE:PS50086};
GN ORFNames=VE00_03808 {ECO:0000313|EMBL:OBT45813.1};
OS Pseudogymnoascus sp. WSF 3629.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1622147 {ECO:0000313|EMBL:OBT45813.1, ECO:0000313|Proteomes:UP000091997};
RN [1] {ECO:0000313|EMBL:OBT45813.1, ECO:0000313|Proteomes:UP000091997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSF 3629 {ECO:0000313|EMBL:OBT45813.1,
RC ECO:0000313|Proteomes:UP000091997};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000091997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSF 3629 {ECO:0000313|Proteomes:UP000091997};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KV454590; OBT45813.1; -; Genomic_DNA.
DR STRING; 1622147.A0A1B8CG62; -.
DR OrthoDB; 76239at2759; -.
DR Proteomes; UP000091997; Unassembled WGS sequence.
DR GO; GO:0016906; F:sterol 3-beta-glucosyltransferase activity; IEA:UniProt.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0030259; P:lipid glycosylation; IEA:InterPro.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR Gene3D; 1.10.10.750; Ypt/Rab-GAP domain of gyp1p, domain 1; 1.
DR Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR InterPro; IPR010610; EryCIII-like_C.
DR InterPro; IPR004276; GlycoTrans_28_N.
DR InterPro; IPR000195; Rab-GAP-TBC_dom.
DR InterPro; IPR035969; Rab-GAP_TBC_sf.
DR InterPro; IPR002213; UDP_glucos_trans.
DR PANTHER; PTHR48050; STEROL 3-BETA-GLUCOSYLTRANSFERASE; 1.
DR PANTHER; PTHR48050:SF13; UDP-GLUCURONOSYLTRANSFERASE; 1.
DR Pfam; PF06722; EryCIII-like_C; 1.
DR Pfam; PF03033; Glyco_transf_28; 1.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
DR SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000091997};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1179..1386
FT /note="Rab-GAP TBC"
FT /evidence="ECO:0000259|PROSITE:PS50086"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 660..692
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 759..795
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 848..1021
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1043..1066
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 660..681
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 773..795
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 885..909
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 993..1019
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1438 AA; 157119 MW; DB5B42CA093B31CE CRC64;
MASKLPPPDQ EKEDQPTVDD APPAYNEATG TLDLSRAGIN AQSNIADDGR IDIQINESDT
QLAEQIQQLN LTAQQETPDH PSPAYTPPSY LVGTPGATPP PLNVVIQVVG SRGDVQPFVA
LGRELKNKYG HRIRLATHGT FKKFVEENGL EFFEIGGDPT ELMAFMVKNP GLLPGMKSLK
DGEVGRRRRG IAEILEGCWK SCADAEEASE ESSNETKGGV KKAPFIAHAI IANPPSFAHI
HCSQKLGIPL HMMFTSPALI PKPKEWGPHI SISGFYFLSS GSDYQPDAEL ADFLAAGPPP
VYIGFGSIVV DDPNAMTKLI FDAVRKTGQR ALVSKGWGGL GGNELDKPDG VFMLGNVPHD
WLFKHVSCVV HHGGAGTMSA GIALGRPTVI VPFFGDQPFW GAMVARAGAG PLPVPYKSLT
ADKLANSILE ALKPETLERA RELGELIRQE DGCKSGAESF HTHLNVDNLR CMMCPQRPAV
WRVKTTGPKK ENVRLSTFAA TVLGNEGILN MNVMKLYRPC EYHIEEQFVL SNLEGPTPGL
SMAGSVAHSL IHLPINIGKA YAGVVTKPYN GAKTGGWRGF RKGLGKGFGD LLFPMRGIVI
GGTTYGLRGA YEAIRRRMGS DTLSFIFAAH FVQGYEEVKA ATEEERLEVL RRWNELAPEL
RKEKTRGSSK SKGKDKHRDG SGPPTPTNGT AASLITTVFT DFRSSKQLEP IKQIHETAHD
IQYTRESRAT ANIASSVAPP FFATNNISTA EYAMNQITPD EESHESSVGM PGSPPDLSLS
SSKSSKSSFH SSYQSDDNGI LADVGHFEDI GLDDAQSEQE IDDFVDELPS HSSDRSMKGR
SRSLASIQRN LTSKGRPAVP GLGPHGRKLA GEGLGLGLAP GSAAPRRTFS TQSMTSLGAM
NGRNRSPSPL TQPGPFPRSP RSPRMSWQSN RERKSAQELE KECDDEDDDI PDECFLQNVP
MSPRPPGERT VDVPPAASVP KEKIKPAGNG TPATPGAQGS LKQDESFHKP TSPSFYTKPG
RAKSWTVALS ELNAEAKSLT EALEAHADEQ LESNQPKRPP FLSDIKRSKS VMSELPLRRN
DVMIDPLPIS KEKMAVLSRT RPSWLPPKDP LEEKRHLKEY QKMMAASMEA EKKREASNSS
DTSRDDTASS LLRIWEDHVL PNWEAATSLK RTRELWWRGI APRSRGAVWD RAIGNELGVS
ESSYNAALRR AKKLEKKLAK GNATADDLVQ GKWFESINRD VTTTYPELRI FRPGGPLSES
LVDVLMAYVM YRSDVGYVDG LSTATALLLL NFPTPAAAFC ALANLLNRPL PLSFHTHDHG
AMSRIHSLVL ETLSAKFPRL YKQLCLTIQI DQQPGPCVNP IFSSLFTKQL SLDVITRLWD
IWVFEGDAVL VRAMVALIGS LETKFYGVTS AREVLAILND STVEGEEEWV MALRDAGR
//
