ID A0A1B8CHV1_9PEZI Unreviewed; 1257 AA.
AC A0A1B8CHV1;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
GN ORFNames=VE00_03376 {ECO:0000313|EMBL:OBT46410.1};
OS Pseudogymnoascus sp. WSF 3629.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1622147 {ECO:0000313|EMBL:OBT46410.1, ECO:0000313|Proteomes:UP000091997};
RN [1] {ECO:0000313|EMBL:OBT46410.1, ECO:0000313|Proteomes:UP000091997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSF 3629 {ECO:0000313|EMBL:OBT46410.1,
RC ECO:0000313|Proteomes:UP000091997};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000091997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSF 3629 {ECO:0000313|Proteomes:UP000091997};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
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DR EMBL; KV454584; OBT46410.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8CHV1; -.
DR STRING; 1622147.A0A1B8CHV1; -.
DR OrthoDB; 1785483at2759; -.
DR Proteomes; UP000091997; Unassembled WGS sequence.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24178:SF9; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24178; MOLTING PROTEIN MLT-4; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 3.
DR Pfam; PF05729; NACHT; 1.
DR SMART; SM00248; ANK; 11.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 6.
DR PROSITE; PS50088; ANK_REPEAT; 6.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000091997}.
FT DOMAIN 380..531
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT REPEAT 906..930
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 940..965
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 974..998
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1008..1033
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1042..1067
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1144..1168
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 1257 AA; 139883 MW; 10392F2301D11C71 CRC64;
MEGGVGDGDN DASEESGVPQ VEYPIHILHD DDEAAVDIVA VHGLGANPKY AWAWLPKNNP
PDNPNYPEQP LNWLKDLLPS KLLSSKLRCR VMTFNYESKW FLDAPQVRLS NISDNLLDSL
RNNRTKATNR PLIFIGHSFG GNLIEQAIVS SRLHSEYKHI AESTVGVIFL GTPHRGSEAA
KWGVLIASLG GLLGSTEKRI LKDLQKQSGT LTDRLHDFSS WLFSESVPVV CYWEQLKTDY
STRVGPLRFM KSMLKEVVVD ETSACIDGHK KISLHTDHFK INKFYGRDDP SFLQVYPEIV
RMAESAEEML GQRRNPTAIL DDRNAQPEQL LKFLRAMKVM SAKDVLSDIK RRKGGRVGNT
CEWILKREEF SAWGAVPDPQ LFFIAGSPGI GKTMMSTFLV DELQKKIERV PGKALAYFFC
DDKDQDRKTP IAILRSLIWQ ILLQKNDLFD KIQPEFDVQG STIVESFSTL WRILDGILRD
ERAGEVFILI DAFDECDKVM RKELLTCIRE LFQSSSTAQT GKFKFLLTSR PENDILEELN
GVGTRLLMNS ASVNNDLSMY IDFTVDQLAK RKGYAPALKE MVQNALKNEA EGTFLWVSLM
VADLEKEPKY NVKHKLKGLP KGLNETYARI LNENISMEAR EDVQFLLLSM VAARRPFKKR
EIASAFAVWK DGLVLSSQDV DEYADICLLC SSIIYLDGGA DDDSATINFC HQSVKDFLLD
GHGESAWYHT SGDRANLALF QVCWTYLVAE DFHRGGLIVR YEIRHGKECC VKVGSRDLKY
LFPKYAFLQY ASEEWEEHAM ANNPVLFDMF TFSSTKDPVK SYPRVLCRLK VDVAYAPTLQ
AAWLLHVAKE GQEGMVALLH ARGANFNVHD TDIRTPLSWA SYGGHEAVVR LILNTGEAWA
DSKDNKGRTP LSWAAKHGHE AITKLLLSIG KADPNSMDRF GRSPLSHAAE GGHGAVARLL
LNAGSIKPDL RDKDGWSPLS YAARNGHEAV TRLLLDIGEV DPNSMDTYGW SPLAYAARGG
HESVARLLLN IGSVDPDLRN IYGQSPLFHA VGHGHEAVVR LLLNIGSVDP DSRNKDGQSP
LSVAATCGLE AIARLLLSID KVEADSMDKS GRSPLSLAAR WGSEAVTGLL LDEGEVEADS
RDKHGQSPLS FAARAGHTGV ARLLLSTGKV EADSKDKKGQ SPLWWTVHGW GIIQERKAIA
ELLLDTGKVE FVAGIAELLD ITSLARTGQV QYIAHTIWPG TLPARHIIEN RSEDGPR
//
