ID A0A1B8CKS2_9PEZI Unreviewed; 448 AA.
AC A0A1B8CKS2;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Transcription factor IIA, alpha/beta subunit {ECO:0008006|Google:ProtNLM};
GN ORFNames=VE00_03230 {ECO:0000313|EMBL:OBT47409.1};
OS Pseudogymnoascus sp. WSF 3629.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1622147 {ECO:0000313|EMBL:OBT47409.1, ECO:0000313|Proteomes:UP000091997};
RN [1] {ECO:0000313|EMBL:OBT47409.1, ECO:0000313|Proteomes:UP000091997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSF 3629 {ECO:0000313|EMBL:OBT47409.1,
RC ECO:0000313|Proteomes:UP000091997};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000091997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSF 3629 {ECO:0000313|Proteomes:UP000091997};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TFIIA subunit 1 family.
CC {ECO:0000256|ARBA:ARBA00010059}.
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DR EMBL; KV454576; OBT47409.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8CKS2; -.
DR STRING; 1622147.A0A1B8CKS2; -.
DR OrthoDB; 9955at2759; -.
DR Proteomes; UP000091997; Unassembled WGS sequence.
DR GO; GO:0005672; C:transcription factor TFIIA complex; IEA:InterPro.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR CDD; cd07976; TFIIA_alpha_beta_like; 2.
DR Gene3D; 1.10.287.100; -; 1.
DR Gene3D; 2.30.18.10; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
DR InterPro; IPR004855; TFIIA_asu/bsu.
DR InterPro; IPR009088; TFIIA_b-brl.
DR PANTHER; PTHR12694; TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1; 1.
DR PANTHER; PTHR12694:SF8; TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1; 1.
DR Pfam; PF03153; TFIIA; 2.
DR SMART; SM01371; TFIIA; 1.
DR SUPFAM; SSF47396; Transcription factor IIA (TFIIA), alpha-helical domain; 1.
DR SUPFAM; SSF50784; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000091997};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT REGION 75..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 183..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 331..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..273
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..295
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..398
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 448 AA; 49254 MW; D06C1A187BB77960 CRC64;
MSNQTVGAVY QQIIRDVVDS SRVDFEEGGV DESVLDELTR VWQQKLTALN VAQFPWDPKP
EVPPAQQQQT MANIPSSMSY PQEPTPAPMQ QQQQQHAPPQ QGQQYMNRPG PPIPAQAPQF
PQMPQMPQMN AGPRIKAEPG LETGGMPPVY TGMGNATTAQ QRAALNLQAS YGARAAASIN
AIQGMPQQGQ PQQQQGLPQQ QQPQQQQAQQ QQMHQAQQRP QGPSIPRPQM TPSQYQQALA
QQAAHQKQQL EQQAKARQQA AAQQGQGAPN GAQHAQTDGG GDDENEDRHR HFGVIKQVGG
DGSEINMGRV ELDGLIRRQI EARGKAMEGG GLMLPLKQHK ASSGGRRERK KAVDVGQTDG
GDDDDDDDDD KVLKAEDDDE DAINSDLDDP DDPKSDDSGD DETPQVMLCM YDKVQRVKNK
WKCVMKDGVL TINGKDYVFH KASGEYEW
//
