ID A0A1B8CNF8_9PEZI Unreviewed; 717 AA.
AC A0A1B8CNF8;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=CAMK protein kinase {ECO:0000313|EMBL:OBT48337.1};
GN ORFNames=VE00_01152 {ECO:0000313|EMBL:OBT48337.1};
OS Pseudogymnoascus sp. WSF 3629.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1622147 {ECO:0000313|EMBL:OBT48337.1, ECO:0000313|Proteomes:UP000091997};
RN [1] {ECO:0000313|EMBL:OBT48337.1, ECO:0000313|Proteomes:UP000091997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSF 3629 {ECO:0000313|EMBL:OBT48337.1,
RC ECO:0000313|Proteomes:UP000091997};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000091997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSF 3629 {ECO:0000313|Proteomes:UP000091997};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. CAMK Ser/Thr
CC protein kinase family. CHEK2 subfamily.
CC {ECO:0000256|ARBA:ARBA00005575}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KV454570; OBT48337.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8CNF8; -.
DR STRING; 1622147.A0A1B8CNF8; -.
DR OrthoDB; 1451820at2759; -.
DR Proteomes; UP000091997; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR44167; OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED; 1.
DR PANTHER; PTHR44167:SF8; OVARIAN-SPECIFIC SERINE_THREONINE-PROTEIN KINASE LOK; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:OBT48337.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000091997};
KW Transferase {ECO:0000313|EMBL:OBT48337.1}.
FT DOMAIN 31..103
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 158..437
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 481..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 590..631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..495
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 496..510
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 592..631
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 717 AA; 81669 MW; C7F7F6A46620EFA9 CRC64;
MAASLVFRSK NNGSDISDQT INIQLYPDKE FTVNRTPDDQ SPSHNVATFV NERNCLNINL
GLISKNHFRI YGIQYEDADG TESMFYCEDT RSANGTYINR YLIGRNNTRS WPFLLSDGDK
IKLKPDFSFK FKQPIERQRE GMDAVQLEEA ASFAKRYSIT DRLLGSGICG KVYLATEVAT
KRQLACKVVN LRAVAAVLED DQANASREQT MRIEGQRLIR EIEILTRVNH PNIIAMKKAF
RSDNTLYLFM ELAPGGDLCS FVSANGGRLT DLDTRVILRQ LTLAVQYLHS VGIVHRDIKP
ENILMMNTAV GYRVVLTDFG CAANLRAMSR MESLVGTFDY VAPEVHRTER LNGTSYTKAV
DMWSLGIVAF CLLTGESLAS YLEMKHISQE DITARLDRIW PDLESATDQA KDFLARLLVL
DPARRMTADE AIAHSWFTSP SEIGRELERL YARSIQGWVP RRDIYRAIEY ITRNELPRRK
ITTPSSQFQV NSDDQHQASQ KERRRSRKPS DYTSSVYFSL DRHTRKHSYR HVRAREATQR
SKQQIINTLN ESGELFVKDG DVSSYTSPSR KRARILLNMV RDVPPTDLFG KASAGVNSQQ
SQSKTSRTFS QSSSDAVTQP DYVDSSQTQL EQPSLLTEEA LSILSSTFGD EARGTRPRRW
STEATHNGYV SDSFYDSLSD EMKGYLKGDH SMKGYLKGDP SMKAYFRRRR LRQRREK
//
